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@ARTICLE{DixonSuen:132799,
      author       = {S. C. Dixon-Suen and C. M. Nagle and A. P. Thrift and P. D.
                      P. Pharoah and A. Ewing and C. L. Pearce and W. Zheng and G.
                      Chenevix-Trench and P. A. Fasching and M. W. Beckmann and D.
                      Lambrechts and I. Vergote and S. Lambrechts and E. Van
                      Nieuwenhuysen and M. A. Rossing and J. A. Doherty and K. G.
                      Wicklund and J. Chang-Claude$^*$ and A. Y. Jung and K. B.
                      Moysich and K. Odunsi and M. T. Goodman and L. R. Wilkens
                      and P. J. Thompson and Y. B. Shvetsov and T. Dörk and T.-W.
                      Park-Simon and P. Hillemanns and N. Bogdanova and R. Butzow
                      and H. Nevanlinna and L. M. Pelttari and A. Leminen and F.
                      Modugno and R. B. Ness and R. P. Edwards and J. L. Kelley
                      and F. Heitz and A. du Bois and P. Harter and I. Schwaab and
                      B. Y. Karlan and J. Lester and S. Orsulic and B. J. Rimel
                      and S. K. Kjær and E. Høgdall and A. Jensen and E. L.
                      Goode and B. L. Fridley and J. M. Cunningham and S. J.
                      Winham and G. G. Giles and F. Bruinsma and R. L. Milne and
                      M. C. Southey and M. A. T. Hildebrandt and X. Wu and K. H.
                      Lu and D. Liang and D. A. Levine and M. Bisogna and J. M.
                      Schildkraut and A. Berchuck and D. W. Cramer and K. L. Terry
                      and E. V. Bandera and S. H. Olson and H. B. Salvesen and L.
                      C. V. Thomsen and R. K. Kopperud and L. Bjorge and L. A.
                      Kiemeney and L. F. A. G. Massuger and T. Pejovic and A.
                      Bruegl and L. S. Cook and N. D. Le and K. D. Swenerton and
                      A. Brooks-Wilson and L. E. Kelemen and J. Lubiński and T.
                      Huzarski and J. Gronwald and J. Menkiszak and N. Wentzensen
                      and L. Brinton and H. Yang and J. Lissowska and C. K.
                      Høgdall and L. Lundvall and H. Song and J. P. Tyrer and I.
                      Campbell and D. Eccles and J. Paul and R. Glasspool and N.
                      Siddiqui and A. S. Whittemore and W. Sieh and V. McGuire and
                      J. H. Rothstein and S. A. Narod and C. Phelan and H. A.
                      Risch and J. R. McLaughlin and H. Anton-Culver and A. Ziogas
                      and U. Menon and S. A. Gayther and S. J. Ramus and A.
                      Gentry-Maharaj and A. H. Wu and M. C. Pike and C.-C. Tseng
                      and J. Kupryjanczyk and A. Dansonka-Mieszkowska and A.
                      Budzilowska and I. K. Rzepecka and P. M. Webb},
      collaboration = {A. O. C. S. Group and O. C. A. Consortium},
      title        = {{A}dult height is associated with increased risk of ovarian
                      cancer: a {M}endelian randomisation study.},
      journal      = {British journal of cancer},
      volume       = {118},
      number       = {8},
      issn         = {1532-1827},
      address      = {Edinburgh},
      publisher    = {Nature Publ. Group},
      reportid     = {DKFZ-2018-00443},
      pages        = {1123 - 1129},
      year         = {2018},
      abstract     = {Observational studies suggest greater height is associated
                      with increased ovarian cancer risk, but cannot exclude bias
                      and/or confounding as explanations for this. Mendelian
                      randomisation (MR) can provide evidence which may be less
                      prone to bias.We pooled data from 39 Ovarian Cancer
                      Association Consortium studies (16,395 cases; 23,003
                      controls). We applied two-stage predictor-substitution MR,
                      using a weighted genetic risk score combining 609
                      single-nucleotide polymorphisms. Study-specific odds ratios
                      (OR) and $95\%$ confidence intervals (CI) for the
                      association between genetically predicted height and risk
                      were pooled using random-effects meta-analysis.Greater
                      genetically predicted height was associated with increased
                      ovarian cancer risk overall (pooled-OR (pOR) = 1.06;
                      $95\%$ CI: 1.01-1.11 per 5 cm increase in height), and
                      separately for invasive (pOR = 1.06; $95\%$ CI:
                      1.01-1.11) and borderline (pOR = 1.15; $95\%$ CI:
                      1.02-1.29) tumours.Women with a genetic propensity to being
                      taller have increased risk of ovarian cancer. This suggests
                      genes influencing height are involved in pathways promoting
                      ovarian carcinogenesis.},
      cin          = {C020},
      ddc          = {610},
      cid          = {I:(DE-He78)C020-20160331},
      pnm          = {313 - Cancer risk factors and prevention (POF3-313)},
      pid          = {G:(DE-HGF)POF3-313},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:29555990},
      doi          = {10.1038/s41416-018-0011-3},
      url          = {https://inrepo02.dkfz.de/record/132799},
}