TY  - JOUR
AU  - Amitay, Efrat
AU  - Niedermaier, Tobias
AU  - Alwers, Elizabeth
AU  - Chang-Claude, Jenny
AU  - Hoffmeister, Michael
AU  - Brenner, Hermann
TI  - Reproductive factors and colorectal cancer risk: A Population-based case-control study.
JO  - JNCI cancer spectrum
VL  - 6
IS  - 4
SN  - 2515-5091
CY  - Oxford
PB  - Oxford University Press
M1  - DKFZ-2022-01144
SP  - pkac042
PY  - 2022
N1  - #EA:C070#LA:C070#LA:C120# / 2022 Jul 1;6(4):pkac042
AB  - Hormone-replacement therapy (HRT) is associated with lower colorectal cancer (CRC) risk among postmenopausal women. However, little is known about effects of lifetime exposure of women to varying levels of estrogen and progesterone through reproductive factors such as parity, use of oral contraceptives (OC), breastfeeding and menstruation on CRC risk.We assessed associations between reproductive factors and CRC risk among 2650 female CRC patients aged 30+ years and 2175 matched controls in a population-based study in Germany, adjusting for potential confounders by multiple logistic regression.Inverse associations with CRC risk were found for numbers of pregnancies (OR per pregnancy=0.91, 95
KW  - breastfeeding (Other)
KW  - colorectal cancer (Other)
KW  - oral contraceptives (Other)
KW  - pregnancy (Other)
KW  - reproductive factors (Other)
KW  - women (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:35642982
DO  - DOI:10.1093/jncics/pkac042
UR  - https://inrepo02.dkfz.de/record/180172
ER  -