TY - JOUR AU - Bernhardt, D. AU - Peeken, J. C. AU - Kehl, V. AU - Eitz, K. AU - Guckenberger, M. AU - Andratschke, N. AU - Mayinger, M. C. AU - Lindel, K. AU - Dieckmann, K. AU - El Shafie, R. AU - Debus, Jürgen AU - Riesterer, O. AU - Rogers, S. AU - Blanck, O. AU - Wolff, R. AU - Grosu, A. AU - Bilger, A. AU - Henkenberens, C. AU - Schulze, K. AU - Gani, C. AU - Müller, A. C. AU - Radlanski, K. AU - Janssen, S. AU - Ferentinos, K. AU - Combs, S. E. TI - Post-Operative Stereotactic Radiotherapy for Resected Brain Metastases: Results of the Multicenter Analysis (AURORA) of the German Working Group 'Stereotactic Radiotherapy'. JO - International journal of radiation oncology, biology, physics VL - 117 IS - 2S SN - 0360-3016 CY - Amsterdam [u.a.] PB - Elsevier Science M1 - DKFZ-2023-01982 SP - e87 - e88 PY - 2023 AB - While the results of prospective studies support the use of postoperative stereotactic radiotherapy (RT) to the resection cavity (RC) as the standard of care after surgery, there are several issues that need to be investigated such as factors for improving local control, risk of leptomeningeal disease and radiation necrosis. Further, the optimal dose and fractionation is still under debate.The working group 'Stereotactic Radiotherapy' of the German Society of Radiation Oncology (DEGRO) analyzed its multi-institutional database with 661 patients who received postoperative stereotactic RT to the RC. Treatment was performed at 13 centers between 2008 and 2021. Patient characteristics, treatment details, and follow-up data including overall survival (OS), local control (LC) were evaluated. Cox Regression and Kaplan-Meier curves with Log-rank Tests were calculated for selected variables.In this retrospective study, overall survival was 61.5 LB - PUB:(DE-HGF)16 C6 - pmid:37786203 DO - DOI:10.1016/j.ijrobp.2023.06.842 UR - https://inrepo02.dkfz.de/record/284393 ER -