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@ARTICLE{Niedermeyer:305541,
      author       = {S. Niedermeyer and M. Schmutzer-Sondergeld and S. V.
                      Kirchleitner and S. Quach and N. L. Albert$^*$ and N. Thon},
      title        = {{PET} imaging pitfall in recurrent oligodendroglioma with
                      drug-resistant epilepsy: illustrative case.},
      journal      = {Journal of neurosurgery / Case lessons},
      volume       = {10},
      number       = {17},
      issn         = {2694-1902},
      address      = {Charlottesville, Va.},
      publisher    = {American Association of Neurological Surgeons},
      reportid     = {DKFZ-2025-02215},
      pages        = {CASE25589},
      year         = {2025},
      abstract     = {MRI and PET imaging using radiolabeled amino acids offer a
                      valuable adjunct for defining the extent of tumor growth in
                      gliomas, assessing treatment response, and distinguishing
                      true progression from pseudoprogression.The authors report
                      the case of a 37-year-old patient with intractable epilepsy
                      and suspected recurrence of an oligodendroglioma. MRI
                      revealed progressive gadolinium enhancement in the right
                      frontal lobe, and both fluorethylthyrosine PET and
                      translocator protein imaging demonstrated high tracer uptake
                      in the same region, raising concern for tumor recurrence and
                      progression. The patient underwent extensive resection of
                      the right frontal lobe beyond contrast enhancement.
                      Postoperatively, seizures were well controlled.
                      Interestingly, histopathological analysis revealed
                      predominantly normal brain tissue next to a limited area of
                      tumor recurrence, demonstrating that the observed MRI and
                      PET abnormalities were seizure-induced changes rather than
                      tumor recurrence.In patients with epileptic seizures, MRI
                      and PET abnormalities may overestimate tumor recurrence and
                      should be interpreted with caution.
                      https://thejns.org/doi/10.3171/CASE25589.},
      keywords     = {PET imaging (Other) / epilepsy (Other) / oligodendroglioma
                      (Other)},
      cin          = {MU01},
      ddc          = {610},
      cid          = {I:(DE-He78)MU01-20160331},
      pnm          = {899 - ohne Topic (POF4-899)},
      pid          = {G:(DE-HGF)POF4-899},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:41144997},
      doi          = {DOI:10.3171/CASE25589},
      url          = {https://inrepo02.dkfz.de/record/305541},
}