TY  - JOUR
AU  - Hlevnjak, Mario
AU  - Heublein, Sabine
AU  - Thewes, Verena
AU  - Wagener, Lukas
AU  - Pixberg, Constantin
AU  - Fremd, Carlo
AU  - Michel, Laura
AU  - Maurer, Christian
AU  - Buschhorn, Lars
AU  - Dikow, Nicola
AU  - Feng, Fangyoumin
AU  - Fröhling, Stefan
AU  - Herold-Mende, Christel
AU  - Hirsch, Steffen
AU  - Hong, Chen
AU  - Hübschmann, Daniel
AU  - Jassowicz, Lena
AU  - Kozyulina, Polina
AU  - Pfütze, Katrin
AU  - Schlenk, Richard F
AU  - Sinn, Hans-Peter
AU  - Smetanay, Katharina
AU  - Springfeld, Christoph
AU  - Stenzinger, Albrecht
AU  - Wagner, Celina
AU  - Wolf, Stephan
AU  - Trumpp, Andreas
AU  - Jäger, Dirk
AU  - Zivanovic, Oliver
AU  - Zapatka, Marc
AU  - Schneeweiss, Andreas
AU  - Lichter, Peter
TI  - Delivering precision oncology in metastatic breast cancer: Clinical impact of comprehensive genomic profiling-The CATCH experience.
JO  - International journal of cancer
VL  - nn
SN  - 0020-7136
CY  - Bognor Regis
PB  - Wiley-Liss
M1  - DKFZ-2025-02261
SP  - nn
PY  - 2025
N1  - DKFZ-ZMBH Alliance / #LA:B060# / epub
AB  - CATCH is a prospective precision oncology registry trial that exploits whole-genome/exome- and RNA-sequencing to enable actionable biomarker detection in metastatic breast cancer (mBC) patients of any subtype. We herein report long-term follow-up of the first 558 patients consecutively recruited into CATCH in a monocentric setting between June 2017 and October 2021. Main outcome measures were the rate of implementation of molecular tumor board (MTB) recommended treatments and treatment response as assessed by disease control rate, objective response rate and PFS ratio. Out of the recruited patients, 412 (54.9
KW  - breast cancer (Other)
KW  - precision oncology (Other)
KW  - real‐world study (Other)
KW  - whole genome sequencing (Other)
KW  - whole transcriptome sequencing (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:41170836
DO  - DOI:10.1002/ijc.70208
UR  - https://inrepo02.dkfz.de/record/305611
ER  -