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@ARTICLE{Intemann:306358,
author = {T. Intemann and K. Kaulke and D.-K. Kipker and V. Lettieri
and C. Stallmann and C. O. Schmidt and M. Bialke and C.
Hampf and D. Stahl and M. Lablans$^*$ and K. Kraywinkel and
S. Bartholomäus and A.-F. Näher and G. Tremper$^*$ and M.
Lambarki$^*$ and S. March and F. Prasser and A. C. Haber and
J. Drepper and I. Schlünder and T. Kirsten and I. Pigeot
and U. Sax and B. Buchner and S. C. Semler and W. Ahrens},
title = {{I}mproving record linkage for health research-how to
overcome deficiencies? [{V}erbesserung des {R}ecord
{L}inkage für die {G}esundheitsforschung in {D}eutschland
– wie können {D}efizite behoben werden?]},
journal = {Bundesgesundheitsblatt, Gesundheitsforschung,
Gesundheitsschutz},
volume = {68},
number = {12},
issn = {0007-5914},
address = {Heidelberg},
publisher = {Springer},
reportid = {DKFZ-2025-02570},
pages = {1440-1449},
year = {2025},
note = {2025 Dec;68(12):1440-1449},
abstract = {Linking different health data at the personal level (record
linkage, RL) allows answering scientific questions that
could otherwise not be answered by a single data source.
Linked data therefore offer great potential for health
research to improve prevention, treatment, and care at the
population level. Personal health data are protected by
strict legal regulations. Its use requires balancing
legitimate interests in protecting personal data and health
benefits. However, current laws and their interpretations in
Germany place severe restrictions on health data RL such
that its potential for improving health outcomes is still to
be leveraged. In Germany, RL is also hindered by the lack of
a unique identifier that enables error-free merging across
different data sources. Overall, there is a lack of
interoperable solutions to perform comprehensive RL across
studies and data sources in a secure environment.In this
article, we propose solutions for the linkage of personal
health data from different sources based on the White Paper
- Verbesserung des Record Linkage für die
Gesundheitsforschung in Deutschland. Our proposed solutions
include, among others, the establishment of a health ID and
the creation of a decentralized federated research data
infrastructure with central components. Although these
proposals are in line with the General Data Protection
Regulation, there is a need for further legal regulation in
specific cases.},
subtyp = {Review Article},
keywords = {Data linkage (Other) / Data sharing (Other) / FAIR
principles (Other) / Research data infrastructure (Other) /
Unique identifier (Other)},
cin = {E260 / HD01},
ddc = {610},
cid = {I:(DE-He78)E260-20160331 / I:(DE-He78)HD01-20160331},
pnm = {315 - Bildgebung und Radioonkologie (POF4-315)},
pid = {G:(DE-HGF)POF4-315},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:41263970},
doi = {10.1007/s00103-025-04153-y},
url = {https://inrepo02.dkfz.de/record/306358},
}