TY  - JOUR
AU  - Weber, Alexander
AU  - Rosenstiel, Philip
TI  - You (bacteria) shall not pass: NLRP6 can sense you!
JO  - The EMBO journal
VL  - nn
SN  - 0261-4189
CY  - [London]
PB  - Nature Publishing Group UK
M1  - DKFZ-2025-02572
SP  - nn
PY  - 2025
N1  - epub
AB  - The ability of intracellular bacteria to spread directly from one cell to the next, avoiding extracellular immune defenses and drugs, is essential for pathogen dissemination and, ultimately, the progression and severity of infection. In this issue of The EMBO Journal, Boegli and colleagues uncover a previously unrecognized role of the enigmatic innate immune sensor NLRP6 in detecting bacteria-induced lysosomal damage and triggering cytokine release or cell death to limit infection.
LB  - PUB:(DE-HGF)16
C6  - pmid:41266654
DO  - DOI:10.1038/s44318-025-00638-3
UR  - https://inrepo02.dkfz.de/record/306360
ER  -