TY  - JOUR
AU  - Haselmann, Jonas
AU  - Roohani, Siyer
AU  - Wasilewski, David
AU  - Onken, Julia
AU  - Capper, David
AU  - Kaul, David
AU  - Ehret, Felix
TI  - The interdisciplinary management of craniopharyngioma - practice patterns, outcomes, and insights.
JO  - BMC cancer
VL  - 25
IS  - 1
SN  - 1471-2407
CY  - London
PB  - BioMed Central
M1  - DKFZ-2025-02648
SP  - 1837
PY  - 2025
N1  - 2025 Nov 28;25(1):1837
AB  - Craniopharyngiomas are rare, mostly benign brain tumors, and their management remains challenging due to the limited data from large cohorts. This study evaluates the practice patterns and outcomes for craniopharyngioma patients managed at a tertiary care center.This retrospective cohort study included patients with histologically confirmed craniopharyngioma treated between 1996 and 2022. Patient, tumor, and treatment variables were analyzed for their association with local control (LC), progression-free survival (PFS), and overall survival (OS) using multivariable Cox regression models.A total of 88 patients were analyzed. The median clinical and radiographic follow-up periods were 62.0 and 42.5 months, respectively. Fifty-three recurrences and twelve deaths were observed. After primary treatment, the 2-, 4, and 6-year LC and PFS rates were 69.1, 50.7, 37.7
KW  - Craniopharyngioma (Other)
KW  - Hypothalamus (Other)
KW  - Neurocognitive deficits (Other)
KW  - Neurosurgery (Other)
KW  - Pediatrics (Other)
KW  - Pituitary gland (Other)
KW  - Quality of life (Other)
KW  - Radiation therapy (Other)
KW  - Radiotherapy (Other)
KW  - Reirradiation (Other)
KW  - Stereotactic radiosurgery (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:41310495
DO  - DOI:10.1186/s12885-025-14991-3
UR  - https://inrepo02.dkfz.de/record/306611
ER  -