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@ARTICLE{Matuschik:307522,
      author       = {L. Matuschik and K. Wineberger and M. Werner and D. A.
                      Ruess$^*$},
      title        = {{A} rare case of biliary adenocarcinoma mimicking an
                      abdominal wall soft tissue tumor.},
      journal      = {Med},
      volume       = {nn},
      issn         = {2666-6340},
      address      = {Amsterdam},
      publisher    = {Elsevier},
      reportid     = {DKFZ-2026-00027},
      pages        = {nn},
      year         = {2025},
      note         = {epub},
      abstract     = {Meckel's diverticulum is a mostly asymptomatic anatomic
                      anomaly of the small intestine. Frequently, ectopic mucosa
                      can be found within, potentially causing complications such
                      as hemorrhage. In $0.5\%-3.2\%$ of symptomatic patients with
                      Meckel's diverticula, a neoplasm is found.Here, we report an
                      extremely rare case of ectopic biliary adenocarcinoma
                      arising from the tip of an incompletely detached Meckel's
                      diverticulum and infiltrating the adjacent abdominal wall in
                      a 79-year-old patient. Moreover, we review the literature on
                      the seldom occurrences of adenocarcinoma in Meckel's
                      diverticula and potential treatment strategies.Initially
                      believed to be a soft tissue tumor of the abdominal wall,
                      biopsy results showed adenocarcinoma with CA19-9 and CK7
                      expression. Hence, open surgery with en bloc oncologic small
                      intestine resection was performed. The patient was
                      discharged with normal bowel passage after an unremarkable
                      postoperative period. Adjuvant chemotherapy was recommended;
                      however, to date, no standard treatment for adenocarcinoma
                      arising from a Meckel's diverticulum has been agreed
                      upon.The successful surgical resection and ongoing
                      disease-free survival highlight the importance of
                      recognizing and managing malignancies in ectopic embryonic
                      remnants. This case contributes valuable insight into the
                      diagnosis, behavior, and treatment considerations of ectopic
                      malignancies.This research has not received any external
                      funding.},
      keywords     = {Meckel’s diverticulum (Other) / adenocarcinoma (Other) /
                      ectopic biliary tissue (Other) / omphalomesenteric duct cyst
                      (Other) / translation to patients (Other)},
      cin          = {FR01},
      ddc          = {610},
      cid          = {I:(DE-He78)FR01-20160331},
      pnm          = {899 - ohne Topic (POF4-899)},
      pid          = {G:(DE-HGF)POF4-899},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:41478282},
      doi          = {10.1016/j.medj.2025.100930},
      url          = {https://inrepo02.dkfz.de/record/307522},
}