%0 Journal Article
%A Becht, Selina
%A Ben Khaled, Najib
%A Schrodi, Simone
%A von Bergwelt-Baildon, Michael
%A Buggisch, Peter
%A Crispin, Alexander
%A Hofmann, Wolf-Peter
%A Marschall, Ursula
%A Mayerle, Julia
%A Mörtl, Bernhard
%A Orabi, Sami
%A Philipp, Alexander
%A Trojan, Jörg
%A Weiglein, Tobias
%A De Toni, Enrico N
%A Berger-Thürmel, Karin
%T What can claims data tell us about risk factors and survival of patients with hepatocellular carcinoma? Insights from a German population-based study.
%J Frontiers in oncology
%V 15
%@ 2234-943X
%C Lausanne
%I Frontiers Media
%M DKFZ-2026-00029
%P 1650982
%D 2025
%X Geographic and temporal variations in the incidence and treatment of chronic viral hepatitis and trends in the development of metabolic and behavioral risk factors result in heterogeneous incidences of hepatocellular carcinoma (HCC). Therefore, national epidemiological information should be evaluated to identify the need for action.This retrospective observational study included adult patients with incident HCC (2016-2020). A network analysis was performed to investigate inter-relationships among risk factor diagnoses before HCC. Kaplan-Meier method and Cox proportional hazard model were used to analyze survival.A total of 2,778 patients were included. Mean age was 71.9 years (SD ±9.7); 69
%K cancer epidemiology (Other)
%K hepatocellular carcinoma (Other)
%K metabolic risk factors (Other)
%K real-world evidence (Other)
%K secondary data (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:41476582
%2 pmc:PMC12750458
%R 10.3389/fonc.2025.1650982
%U https://inrepo02.dkfz.de/record/307524