DKFZ 13 records found  1 - 10next  jump to record: Search took 0.00 seconds. 
DBCoverage [DKFZ-2023-00480] Journal Article
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Food processing and cancer risk in Europe: results from the prospective EPIC cohort study.
Food processing has been hypothesised to play a role in cancer development; however, data from large-scale epidemiological studies are scarce. This study investigated the association between dietary intake according to amount of food processing and risk of cancer at 25 anatomical sites using data from the European Prospective Investigation into Cancer and Nutrition (EPIC) study.This study used data from the prospective EPIC cohort study, which recruited participants between March 18, 1991, and July 2, 2001, from 23 centres in ten European countries. [...]
[DKFZ-2023-00308] Journal Article
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Dietary intake of total, heme and non-heme iron and the risk of colorectal cancer in a European prospective cohort study.
Iron is an essential micronutrient with differing intake patterns and metabolism between men and women. Epidemiologic evidence on the association of dietary iron and its heme and non-heme components with colorectal cancer (CRC) development is inconclusive.We examined baseline dietary questionnaire-assessed intakes of total, heme, and non-heme iron and CRC risk in the EPIC cohort. [...]
[DKFZ-2022-01471] Journal Article
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Diet-wide association study of 92 foods and nutrients and lung cancer risk in the European Prospective Investigation into Cancer and Nutrition study and the Netherlands Cohort Study.
It is unclear whether diet, and in particular certain foods or nutrients, are associated with lung cancer risk. We assessed associations of 92 dietary factors with lung cancer risk in 327,790 participants in the European Prospective Investigation into Cancer and Nutrition (EPIC). [...]
[DKFZ-2022-00286] Journal Article
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Serum markers of biological ageing provide long-term prediction of life expectancy-a longitudinal analysis in middle-aged and older German adults.
Age & ageing 51(2), afab271 () [10.1093/ageing/afab271]  GO
lifestyle behaviours and chronic co-morbidities are leading risk factors for premature mortality and collectively predict wide variability in individual life expectancy (LE). We investigated whether a pre-selected panel of five serum markers of biological ageing could improve predicting the long-term mortality risk and LE in middle-aged and older women and men.we conducted a case-cohort study (n = 5,789 among which there were 2,571 deaths) within the European Prospective Investigation into Cancer-Heidelberg cohort, a population cohort of middle-aged and older individuals, followed over a median duration of 18 years. [...]
[DKFZ-2021-03232] Journal Article
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Ageing-related markers and risks of cancer and cardiovascular disease: a prospective study in the EPIC-Heidelberg cohort.
Biological age is an important risk factor for chronic diseases. We examined the associations between five markers of unhealthy ageing; Growth Differentiation Factor-15 (GDF-15), N-terminal pro-brain natriuretic peptide (NT-proBNP), glycated hemoglobin A1c (HbA1C), C-Reactive Protein (CRP) and cystatin-C; with risks of cancer and cardiovascular disease (CVD). [...]
DBCoverage [DKFZ-2021-02288] Journal Article
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Food biodiversity and total and cause-specific mortality in 9 European countries: An analysis of a prospective cohort study.
PLoS medicine 18(10), e1003834 - () [10.1371/journal.pmed.1003834]  GO
Food biodiversity, encompassing the variety of plants, animals, and other organisms consumed as food and drink, has intrinsic potential to underpin diverse, nutritious diets and improve Earth system resilience. Dietary species richness (DSR), which is recommended as a crosscutting measure of food biodiversity, has been positively associated with the micronutrient adequacy of diets in women and young children in low- and middle-income countries (LMICs). [...]
[DKFZ-2021-01924] Journal Article
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Consumption of ultra-processed foods associated with weight gain and obesity in adults: A multi-national cohort study.
Clinical nutrition 40(9), 5079 - 5088 () [10.1016/j.clnu.2021.08.009]  GO
There is a worldwide shift towards increased consumption of ultra-processed foods (UPF) with concurrent rising prevalence of obesity. We examined the relationship between the consumption of UPF and weight gain and risk of obesity.This prospective cohort included 348 748 men and women aged 25-70 years. [...]
[DKFZ-2021-01098] Journal Article
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Dietary intake of advanced glycation endproducts and risk of hepatobiliary cancers: A multinational cohort study.
Advanced glycation endproducts (AGEs) may contribute to liver carcinogenesis because of their proinflammatory and prooxidative properties. Diet is a major source of AGEs, but there is sparse human evidence on the role of AGEs intake in liver cancer etiology. [...]
[DKFZ-2021-00956] Journal Article
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A prospective diet-wide association study for risk of colorectal cancer in EPIC.
Evidence regarding the association of dietary exposures with colorectal cancer (CRC) risk is not consistent with a few exceptions. Therefore, we conducted a diet-wide association study (DWAS) in the European Prospective Investigation into Cancer and Nutrition (EPIC) to evaluate the associations between several dietary exposures with CRC risk.The association of 92 food and nutrient intakes with CRC risk was assessed in 386,792 participants, 5,069 of whom developed incident CRC. [...]

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