DKFZ 4 records found  Search took 0.00 seconds. 
DBCoverage [DKFZ-2021-01662] Journal Article (Review Article)
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Development of Randomized Trials in Adults with Medulloblastoma-The Example of EORTC 1634-BTG/NOA-23.
Cancers 13(14), 3451 () [10.3390/cancers13143451]  GO
Medulloblastoma is a rare brain malignancy. Patients after puberty are rare and bear an intermediate prognosis. [...]
[DKFZ-2019-01161] Journal Article
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Imaging necrosis during treatment is associated with worse survival in EORTC 26101 study.
Neurology 92(24), e2754-e2763 () [10.1212/WNL.0000000000007643]  GO
Imaging necrosis on MRI scans was assessed and compared to outcome measures of the European Organisation for Research and Treatment of Cancer 26101 phase III trial that compared single-agent lomustine with lomustine plus bevacizumab in patients with progressive glioblastoma.MRI in this post hoc analysis was available for 359 patients (lomustine = 127, lomustine + bevacizumab = 232). First, imaging necrosis at baseline being formally measurable (>10 × 10 mm, given 2 slices) was assessed. [...]
[DKFZ-2017-05475] Journal Article
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Health-related quality of life in patients with high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study.
Temozolomide chemotherapy versus radiotherapy in patients with a high-risk low-grade glioma has been shown to have no significant effect on progression-free survival. If these treatments have a different effect on health-related quality of life (HRQOL), it might affect the choice of therapy. [...]

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