DKFZ 10 records found  Search took 0.00 seconds. 
DBCoverage [DKFZ-2023-00260] Journal Article
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Local control and patient reported outcomes after online MR guided stereotactic body radiotherapy of liver metastases.
Stereotactic body radiotherapy (SBRT) is used to treat liver metastases with the intention of ablation. High local control rates were shown. [...]
pmc [DKFZ-2022-03124] Journal Article
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AP4 is a mediator of epithelial-mesenchymal transition and metastasis in colorectal cancer.
The basic helix-loop-helix transcription factor AP4/TFAP4/AP-4 is encoded by a c-MYC target gene and displays up-regulation concomitantly with c-MYC in colorectal cancer (CRC) and numerous other tumor types. Here a genome-wide characterization of AP4 DNA binding and mRNA expression was performed using a combination of microarray, genome-wide chromatin immunoprecipitation, next-generation sequencing, and bioinformatic analyses. [...]
DBCoverage [DKFZ-2022-03052] Journal Article
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Dose-escalated radiotherapy with simultaneous integrated boost for bone metastases in selected patients with assumed favourable prognosis.
Radiology and oncology 56(4), 515 - 524 () [10.2478/raon-2022-0053]  GO
Stereotactic body radiotherapy (SBRT) concepts for dose escalation are increasingly used for bone metastases in patients with oligometastatic or oligoprogressive disease. For metastases that are not suitable for SBRT-regimens, a treatment with 30/40 Gy with simultaneous integrated boost (SIB) in 10 fractions represents a possible regimen. [...]
[DKFZ-2022-02390] Journal Article
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Ultrasonic bone cement removal efficiency in total joint arthroplasty revision - a computer tomographic-based cadaver study.
Polymethylmethacrylate removal during septic total joint arthroplasty revision is associated with a high fracture and perforation risk. Ultrasonic cement removal is considered a bone-preserving technique. [...]
[DKFZ-2022-01925] Journal Article
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Attitudes and perceptions of radiologists towards online (virtual) oncologic multidisciplinary team meetings during the COVID-19 pandemic-a survey of the European Society of Oncologic Imaging (ESOI).
European radiology 33(2), 1194-1204 () [10.1007/s00330-022-09083-w]  GO
To explore radiologists' opinions regarding the shift from in-person oncologic multidisciplinary team meetings (MDTMs) to online MDTMs. To assess the perceived impact of online MDTMs, and to evaluate clinical and technical aspects of online meetings.An online questionnaire including 24 questions was e-mailed to all European Society of Oncologic Imaging (ESOI) members. [...]
[DKFZ-2021-01834] Journal Article
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Genetic insights into biological mechanisms governing human ovarian ageing.
Nature <London> 596(7872), 393-397 () [10.1038/s41586-021-03779-7]  GO
Reproductive longevity is essential for fertility and influences healthy ageing in women1,2, but insights into its underlying biological mechanisms and treatments to preserve it are limited. Here we identify 290 genetic determinants of ovarian ageing, assessed using normal variation in age at natural menopause (ANM) in about 200,000 women of European ancestry. [...]
[DKFZ-2020-02417] Journal Article
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Joint Imaging Platform for Federated Clinical Data Analytics.
Image analysis is one of the most promising applications of artificial intelligence (AI) in health care, potentially improving prediction, diagnosis, and treatment of diseases. Although scientific advances in this area critically depend on the accessibility of large-volume and high-quality data, sharing data between institutions faces various ethical and legal constraints as well as organizational and technical obstacles.The Joint Imaging Platform (JIP) of the German Cancer Consortium (DKTK) addresses these issues by providing federated data analysis technology in a secure and compliant way. [...]
[DKFZ-2020-01726] Journal Article
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Involvement of radiologists in oncologic multidisciplinary team meetings: an international survey by the European Society of Oncologic Imaging.
Multidisciplinary tumour boards (MTBs) play an increasingly important role in managing cancer patients from diagnosis to treatment. However, many problems arise around the organisation of MTBs, both in terms of organisation-administration and time management. [...]
[DKFZ-2019-00043] Journal Article (Erratum/Correction)
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Correction to: FDG-PET/MRI in patients with pelvic recurrence of rectal cancer: first clinical experiences.
European radiology 29(2), 1064 - 1064 () [10.1007/s00330-018-5677-7]  GO
The original version of this article, published on 6 July 2018, unfortunately contained a mistake..
[DKFZ-2019-00037] Journal Article
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FDG-PET/MRI in patients with pelvic recurrence of rectal cancer: first clinical experiences.
European radiology 29(1), 422 - 428 () [10.1007/s00330-018-5589-6]  GO
To determine the value of 18F-FDG-PET/MRI in the diagnosis and management of patients with pelvic recurrence of rectal cancer.Forty-four patients (16 women, 28 men) with a history of rectal cancer who received FDG-PET/MRI between June 2011 and February 2017 at our institution were retrospectively enrolled. Three patients received two FDG-PET/MRIs; thus a total of 47 examinations were included. [...]

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