DKFZ 4 records found  Search took 0.01 seconds. 
DBCoverage [DKFZ-2022-02551] Journal Article
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Common variability in oestrogen-related genes and pancreatic ductal adenocarcinoma risk in women
The incidence of pancreatic ductal adenocarcinoma (PDAC) is different among males and females. This disparity cannot be fully explained by the difference in terms of exposure to known risk factors; therefore, the lower incidence in women could be attributed to sex-specific hormones. [...]
DBCoverage [DKFZ-2021-03217] Journal Article
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Identification of Recessively Inherited Genetic Variants Potentially Linked to Pancreatic Cancer Risk.
Although 21 pancreatic cancer susceptibility loci have been identified in individuals of European ancestry through genome-wide association studies (GWASs), much of the heritability of pancreatic cancer risk remains unidentified. A recessive genetic model could be a powerful tool for identifying additional risk variants. [...]
[DKFZ-2021-02237] Journal Article
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Genetic polymorphisms involved in mitochondrial metabolism and pancreatic cancer risk.
The mitochondrial metabolism has been associated with pancreatic ductal adenocarcinoma (PDAC) risk. Recent evidence also suggests the involvement of the genetic variability of the mitochondrial function in several traits involved in PDAC aetiology. [...]
DBCoverage [DKFZ-2021-02176] Journal Article
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Association of Genetic Variants Affecting microRNAs and Pancreatic Cancer Risk.
Genetic factors play an important role in the susceptibility to pancreatic cancer (PC). However, established loci explain a small proportion of genetic heritability for PC; therefore, more progress is needed to find the missing ones. [...]

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