Home > Search Results: author:"Kuonen, F."
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1.
DBCoverage [DKFZ-2022-01467] Journal Article
; ; ; et al
The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors.
Nature Communications 13(1), 4061 () [10.1038/s41467-022-31574-z]  GO
Most lncRNAs display species-specific expression patterns suggesting that animal models of cancer may only incompletely recapitulate the regulatory crosstalk between lncRNAs and oncogenic pathways in humans. Among these pathways, Sonic Hedgehog (SHH) signaling is aberrantly activated in several human cancer entities. [...]
ddc:500
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