Books

Molecular imaging with positron emission tomography (PET) using tumour-targeting radiopharmaceuticals has gained widespread acceptance in oncology with numerous clinical applications. The hybrid imaging modality PET/CT (computed tomography) allows simultaneous assessment of both molecular and morphologic information. [...]

Noninvasive magnetic resonance imaging (MRI) techniques are increasingly applied in the clinic with a fast-growing body of evidence regarding their value in diagnostic radiology. In contrast to biochemical or histological markers, the key advantages of imaging biomarkers are the noninvasive nature and the spatial and temporal resolution of these approaches. [...]

Defining artificial intelligence (AI) remains a complex challenge, given its rapidly evolving nature. Nevertheless, one broadly accepted definition-endorsed by the European Union-describes AI as a suite of algorithms that learn from data to make predictions. [...]

Targeted therapies are applied to increase the efficiency of antitumor treatment by simultaneously decreasing side effects. This can be achieved using carrier molecules that specifically bind to target structures or areas with remodeling activity. [...]

Magnetic resonance imaging is characterized by high spatial resolution and unsurpassed soft tissue discrimination. Development and characterization of both intrinsic and extrinsic magnetic resonance (MR) imaging probes in the last decade has further strengthened the pivotal role MR imaging holds in the assessment of cancer in preclinical and translational settings. [...]

The evolving possibilities of molecular imaging (MI) are fundamentally changing the way we look at cancer, with imaging paradigms now shifting away from basic morphological measures toward the longitudinal assessment of functional, metabolic, cellular, and molecular information in vivo. Recent developments of imaging methodology and probe molecules utilizing the vast number of novel animal models of human cancers have enhanced our ability to non-invasively characterize neoplastic tissue, the tumor microenvironment (TME), and follow anticancer treatments. [...]

Die Memoiren von Prof. Dr. [...]

RNA-binding proteins are key mediators of many of the RNA-regulatory functions throughout the RNA life cycle in the nucleus and in the cytoplasm. The invention and the recent refinement of the RNA-interactome capture technology has now enabled the analysis of the global RNA-interactome in living cells in the nucleus and in the cytoplasm separately. [...]