Reports

This white paper was authored by the Working Group on Best Practices for Safety Testing of Experimental RF Hardware of the International Society for Magnetic Resonance in Medicine (ISMRM). Its purpose is 'to assist experts in MRI scanner hardware with obtaining local research ethics approvals for radio frequency (RF) devices built at the research site'. [...]

The main argument for the use of ion beams (protons or carbon ions) in radiotherapy is their ability to lower the depositeddose to surrounding healthy organs, because of the Bragg peak. However, due to the steep dose gradient at the distal edgeof the Bragg peak, uncertainties in the determination of ion range can have a profound impact on organs adjacent to the tumor.Incorrect range predictions may cause an overshoot or undershoot of the Bragg peak respectively lowering the tumordose or increasing the delivered dose to adjacent organ.Clinically the uncertainty in the range predictions is accounted for by adding a margin around the tumor to address all possibleshifts of the Bragg peak. [...]