Publications database

Objective.Adaptive radiotherapy (ART) requires robust end-to-end (E2E) testing tools capable of reproducing organ deformation, physiological motion, and multimodal imaging properties. TheToraco-abdominalAnthropomorphic Phantom withMotion forAdaptiveRadiotherapy (TAM-ARa) is a dynamic anthropomorphic phantom developed to support the design, validation, and quality assurance of online ART workflows.Approach.The phantom was constructed with anatomically realistic bone, lung, and abdominal organ models fabricated from tissue equivalent materials. [...]

Sézary syndrome (SS) is a rare neoplasm associated with poor prognosis. Due to the rarity of the disease, large-scale investigations are scarce, while identifying prognostic factors is essential for improving treatment outcomes. [...]

The local immune effects of cancer radiotherapy remain poorly characterized in humans due to limited access to irradiated tissue. Mechanistic insights largely derive from preclinical models employing tumor-intact, neoadjuvant-like settings. [...]

Convolutional neural networks (CNNs) can rapidly predict channel-wise B 1 + $$ {B}_1^{+} $$ maps from 7T localizer images, reducing acquisition time to seconds. This paper investigates if a CNN trained on one site's data can generalize to predict B 1 + $$ {B}_1^{+} $$ maps for brain imaging at unseen sites supporting the feasibility of a universal network for subject-specific B 1 + $$ {B}_1^{+} $$ - mapping. [...]

Gallium-67 remains a relevant radionuclide for single-photon emission computed tomography (SPECT) and radiopharmaceutical development as a longer-lived 68Ga surrogate. In this work, the use of gold and gold-coated aluminum backings was evaluated for the cyclotron-based production of this radionuclide via the 68Zn(p,2n)67Ga nuclear reaction. [...]

Circulating tumor DNA (ctDNA) is a promising biomarker in melanoma, with higher sensitivity for tumor burden detection than conventional diagnostics. While well established in research, clinical routine implementation remains pending. [...]

Men with a family history of prostate cancer (PCa) or a pathogenic germline variant (PGV) face increased PCa risk. However, structured PCa early detection and insights into the experiences of affected men remain limited. [...]

How premalignant tissue transforms into cancer remains an open question. In this issue of Cancer Cell, Zhang et al. [...]