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2025-12-12
13:36

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2025-12-12
13:35

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2025-12-11
17:38

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2025-12-11
17:34

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2025-12-11
17:28

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2025-12-11
16:12
[DKFZ-2025-02897] Dissertation / PhD Thesis

Rolle der endothelialen Indolamin-2,3-Dioxygenase in der Immunregulation von Gliomen und Multiple Sklerose
Dissertation, Universität Heidelberg, 2025  GO

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2025-12-11
15:04
DBCoverage [DKFZ-2025-02895] Journal Article
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Outcomes and recurrence pattern analysis of intensity modulated chemoradiotherapy in nasopharyngeal cancer: a retrospective study from Heidelberg University Hospital.
To evaluate treatment outcomes, toxicity, and recurrence patterns by dose level in nasopharyngeal carcinoma (NPC) patients treated with intensity-modulated radiotherapy (IMRT) and weekly cisplatin.We retrospectively analyzed 48 NPC patients treated between 2005 and 2019 with IMRT and weekly cisplatin (40 mg/m²). The planning target volume (PTV) received a median total dose of 57.6 Gy (1.8 Gy/fraction) with a simultaneous integrated boost to the primary tumor and nodal metastases up to 70.4 Gy. [...]

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2025-12-11
15:01
DBCoverage [DKFZ-2025-02894] Journal Article
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Advancing the prediction of factors associated with bipolar disorder risk: utilizing early recognition tools and polygenic risk scores.
Bipolar disorder (BD) is a highly heritable mental illness that affects ∼ 1-2% of the world's population and has complex genetic and environmental underpinnings. Early detection is critical to improving treatment outcomes, but current strategies have limited predictive power. [...]

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2025-12-11
14:56
[DKFZ-2025-02893] Journal Article
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Lactic acid promotes an MDSC-like phenotype via HIF1α stabilization with impact on prognosis in renal cell carcinoma.
Paradoxically, immune cell infiltration correlates with worse prognosis in renal cell carcinoma (RCC) patients, with tumor-associated myeloid cells playing a key role in tumor progression. However, little is known about factors driving their polarization. [...]

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2025-12-11
14:53

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