B086
Modellierung Biol. Systeme
Also known as:B086 Modellierung Biol. Systeme; Theoretische Systembiologie
| ID | I:(DE-He78)B086-20160331 |
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Journal Article
Weber, P. A. A. ; Perro, M. ; Nicolini, V. G. ; Hatje, K. ; Jenni, S. ; Briner, S. ; Bommer, E. ; Tanner, M. ; Pilet, S. ; Hüsser, T. ; Yángüez, E. ; Chen, S. ; Peixoto, A. ; Dekhtiarenko, I. ; Lauener, L. ; Herter, S. ; Höfer, T.DKFZ* ; Hage, C. ; Majety, M. ; Bacac, M. ; Colombetti, S. ; Leclair, S. ; Seeber, S. ; Mücke, M. ; Umaña, P. ; Klein, C. ; Codarri Deak, L.
Tobemstomig, a novel bispecific antibody, preferentially blocks PD-1 and LAG-3 on CD8 TILs to expand stem-like T-cells for sustained tumor control.
Cancer research communications nn, nn (2026) [10.1158/2767-9764.CRC-26-0207]2026
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Rodríguez-Correa, E. (First author)DKFZ* ; Grünschläger, F. (First author)DKFZ* ; Nizharadze, T. (First author)DKFZ* ; Anstee, N. S.DKFZ* ; Al-Sabah, J.DKFZ* ; Kumpost, V. ; Sedlmeier, A.DKFZ* ; Li, C.DKFZ* ; Ball, M.DKFZ* ; Fotopoulou, F.DKFZ* ; Jayarajan, J.DKFZ* ; Ghezzi, I.DKFZ* ; Knoch, J.DKFZ* ; Druce, M. C.DKFZ* ; Aurich, K.DKFZ* ; Büchler-Schäff, M.DKFZ* ; Lux, S.DKFZ* ; Hernández-Malmierca, P.DKFZ* ; Gräsel, J.DKFZ* ; Vonficht, D.DKFZ* ; López-Osias, M. ; González-Saiz, E. ; Fernández-Pérez, D. ; Mathioudaki, A.DKFZ* ; Zaugg, J. ; Rodríguez-Fraticelli, A. ; Mikut, R. ; Trumpp, A.DKFZ* ; Höfer, T.DKFZ* ; Hübschmann, D.DKFZ* ; Haas, S. ; Milsom, M. (Last author)DKFZ*
A kinetics-based model of haematopoiesis reveals extrinsic regulation of skewed lineage output from stem cells.
Nature cell biology 28(6), 1127-1140 (2026) [10.1038/s41556-026-01958-0]2026
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Meyer, T. ; Lamprecht, F.DKFZ* ; Begitt, A. ; Höfer, T.DKFZ* ; Vinkemeier, U.
Nuclear export block of tyrosine-phosphorylated STAT1 facilitates rapid responsiveness to interferon-γ stimuli at the expense of signal strength.
Biochimica et biophysica acta / Gene regulatory mechanisms 1869(2), 195151 (2026) [10.1016/j.bbagrm.2026.195151]2026
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Wölbert, L. C. (First author)DKFZ* ; Busa, V. (First author)DKFZ* ; Danson, A. (First author)DKFZ* ; Fernández Torices, S.DKFZ* ; Sood, S.DKFZ* ; Lammers, F.DKFZ* ; Knoch, J.DKFZ* ; Ball, M.DKFZ* ; Fotopoulou, F.DKFZ* ; Rodriguez Correa, E.DKFZ* ; Schneider, A.DKFZ* ; Coraggio, F.DKFZ* ; Kuck, A.DKFZ* ; Del Prete, S.DKFZ* ; Claudino, N.DKFZ* ; Koch, M.-L.DKFZ* ; Cleland, J. P.DKFZ* ; Jayarajan, J.DKFZ* ; Pilz, F.DKFZ* ; Borgers, H.DKFZ* ; Jolly, A.DKFZ* ; Höfer, T. (Last author)DKFZ* ; Milsom, M. (Last author)DKFZ* ; Essers, M. (Last author)DKFZ* ; Odom, D. (Last author)DKFZ*
Concentrating cell-type-specific transcriptional signatures in bone marrow from interspecies comparisons.
Cell genomics nn, nn (2026) [10.1016/j.xgen.2026.101365]2026
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Binder, P. (First author)DKFZ* ; Kudulytė, A. ; Klaus, S. ; Höfer, T.DKFZ* ; Schwarz, U. S. ; Ganter, M. ; Becker, N. B. (Last author)DKFZ*
Competitive resource allocation drives asynchronous and rapid nuclear multiplication in the malaria parasite.
Nature Communications 17(1), 7413 (2026) [10.1038/s41467-026-75378-x]2026
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Iozzo, M. ; Ippolito, L. ; Pranzini, E. ; Romagnoli, S. ; Gangarossa, G. ; Grillo, C. ; Roccabianca, S. ; Sandrini, G.DKFZ* ; Benelli, M. ; Comito, G. ; Giannoni, E. ; Chiarugi, P.
Lactate-induced H3K4me3 histone mark promotes PLOD1-driven prostate cancer invasion.
Cell death & disease 17(1), 843 (2026) [10.1038/s41419-026-09091-4]2026
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Kamimae-Lanning, A. N. ; Brown, J. M. ; Günther, M.DKFZ* ; Esau, F.DKFZ* ; Russell, H. ; Larcher, L. ; Langevin, F. ; Isobe, T. ; Wilson, N. K. ; Dingler, F. A. ; Cordell, R. L. ; Wang, M. ; Millington, C. L. ; Claudino, N.DKFZ* ; Gogola, E. ; Nicholls, M. ; Körber, V. ; Göttgens, B. ; de Bruijn, M. F. T. R. ; Garaycoechea, J. I. ; Soulier, J. ; Höfer, T.DKFZ* ; Patel, K. J.
Metabolite-induced DNA damage drives stochastic stem cell loss and clonal hematopoiesis.
Cell stem cell 33(4), 642-659.e11 (2026) [10.1016/j.stem.2026.02.011]2026
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Patil, S. (First author)DKFZ* ; Nöbel, S. ; Gokhale, C. S.
Phenotypic polymorphism via mate copying.
Proceedings of the National Academy of Sciences of the United States of America 123(9), e2510849123 (2026) [10.1073/pnas.2510849123]2026
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Patil, S. (First author)DKFZ* ; Ahmed, A. ; Viossat, Y. ; Noble, R.
Preventing evolutionary rescue in cancer using two-strike therapy.
Genetics 232(2), iyaf255 (2026) [10.1093/genetics/iyaf255]2026
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Corazzi, L. (First author)DKFZ* ; Ing, A. (First author)DKFZ* ; Benito, E. ; Cosenza, M. R. ; Hasenfeld, P. ; Weber, T. ; Marx, A. J. M.DKFZ* ; Ionasz, V.DKFZ* ; Trausch, N.DKFZ* ; Benedetto, S.DKFZ* ; Di Muzio, G.DKFZ* ; Ding, B.DKFZ* ; Berlanda, J.DKFZ* ; Giaisi, M.DKFZ* ; Claudino, N.DKFZ* ; Höfer, T.DKFZ* ; Korbel, J. O.DKFZ* ; Wei, P.-C. (Last author)DKFZ*
Recurrent DNA break clusters drive replication-stress-induced copy number variants and genome diversification.
Nature Communications 17(1), 3627 (2026) [10.1038/s41467-026-71790-5]2026
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