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B086
Modellierung Biol. Systeme Also known as:B086 Modellierung Biol. Systeme; Theoretische Systembiologie| ID | I:(DE-He78)B086-20160331 |
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Journal Article
Tobemstomig, a novel bispecific antibody, preferentially blocks PD-1 and LAG-3 on CD8 TILs to expand stem-like T-cells for sustained tumor control.
Cancer research communications nn, nn (2026) [10.1158/2767-9764.CRC-26-0207]
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A kinetics-based model of haematopoiesis reveals extrinsic regulation of skewed lineage output from stem cells.
Nature cell biology 28(6), 1127-1140 (2026) [10.1038/s41556-026-01958-0]
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Nuclear export block of tyrosine-phosphorylated STAT1 facilitates rapid responsiveness to interferon-γ stimuli at the expense of signal strength.
Biochimica et biophysica acta / Gene regulatory mechanisms 1869(2), 195151 (2026) [10.1016/j.bbagrm.2026.195151]
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Lactate-induced H3K4me3 histone mark promotes PLOD1-driven prostate cancer invasion.
Cell death & disease nn, nn (2026) [10.1038/s41419-026-09091-4]
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Metabolite-induced DNA damage drives stochastic stem cell loss and clonal hematopoiesis.
Cell stem cell 33(4), 642-659.e11 (2026) [10.1016/j.stem.2026.02.011]
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Phenotypic polymorphism via mate copying.
Proceedings of the National Academy of Sciences of the United States of America 123(9), e2510849123 (2026) [10.1073/pnas.2510849123]
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Preventing evolutionary rescue in cancer using two-strike therapy.
Genetics 232(2), iyaf255 (2026) [10.1093/genetics/iyaf255]
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Recurrent DNA break clusters drive replication-stress-induced copy number variants and genome diversification.
Nature Communications 17(1), 3627 (2026) [10.1038/s41467-026-71790-5]
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Detecting and quantifying clonal selection in somatic stem cells.
Nature genetics 57(7), 1718-1729 (2025) [10.1038/s41588-025-02217-y]
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Embryonic macrophages orchestrate niche cell homeostasis for the establishment of the definitive hematopoietic stem cell pool.
Nature Communications 16(1), 4428 (2025) [10.1038/s41467-025-59059-9]
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