B086
B086 Modellierung Biol. Systeme
Also known as:Theoretische Systembiologie
| ID | I:(DE-He78)B086-20160331 |
Recent Publications
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Journal Article
Körber, V. (First author)DKFZ* ; Jakobsen, N. A. ; Ansari-Pour, N. ; Moore, R. ; Claudino, N.DKFZ* ; Metzner, M. ; Thielecke, E.DKFZ* ; Esau, F.DKFZ* ; Usukhbayar, B. ; Salazar, M. A. ; Newman, S. ; Kendrick, B. J. L. ; Taylor, A. H. ; Afinowi-Luitz, R. ; Gundle, R. ; Watkins, B. ; Wheway, K. ; Beazley, D. ; Dakin, S. G. ; Palmer, A. ; Carr, A. J. ; Vyas, P. ; Höfer, T. (Last author)DKFZ*
Detecting and quantifying clonal selection in somatic stem cells.
Nature genetics 57(7), 1718-1729 (2025) [10.1038/s41588-025-02217-y]2025
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Journal Article
Perçin, G. ; Riege, K. ; Fröbel, J. ; Metz, J.DKFZ* ; Culemann, S. ; Lesche, M. ; Reinhardt, S. ; Höfer, T.DKFZ* ; Hoffmann, S. ; Waskow, C.
Embryonic macrophages orchestrate niche cell homeostasis for the establishment of the definitive hematopoietic stem cell pool.
Nature Communications 16(1), 4428 (2025) [10.1038/s41467-025-59059-9]2025
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Journal Article
Okonechnikov, K. (First author)DKFZ* ; Joshi, P. K. (First author)DKFZ* ; Körber, V. (First author)DKFZ* ; Rademacher, A.DKFZ* ; Bortolomeazzi, M.DKFZ* ; Mallm, J.-P.DKFZ* ; Vaillant, J.DKFZ* ; da Silva, P. B. G.DKFZ* ; Statz, B.DKFZ* ; Sepp, M. ; Sarropoulos, I. ; Yamada, T. ; Wittmann, A.DKFZ* ; Schramm, K.DKFZ* ; Blattner-Johnson, M.DKFZ* ; Fiesel, P.DKFZ* ; Jones, B.DKFZ* ; Jäger, N.DKFZ* ; Milde, T.DKFZ* ; Pajtler, K.DKFZ* ; van Tilburg, C. M.DKFZ* ; Witt, O.DKFZ* ; Bochennek, K. ; Weber, K. J.DKFZ* ; Nonnenmacher, L. ; Reimann, C. ; Ghasemi, D. R.DKFZ* ; Schüller, U. ; Mynarek, M. ; Rutkowski, S. ; Jones, D.DKFZ* ; Korshunov, A.DKFZ* ; Rippe, K.DKFZ* ; Westermann, F.DKFZ* ; Thongjuea, S.DKFZ* ; Höfer, T.DKFZ* ; Kaessmann, H.DKFZ* ; Kutscher, L. (Last author)DKFZ* ; Pfister, S. (Last author)DKFZ*
Oncogene aberrations drive medulloblastoma progression, not initiation.
Nature 642(8069), 1062-1072 (2025) [10.1038/s41586-025-08973-5]2025
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Journal Article
Patil, S. (First author)DKFZ* ; Ahmed, A. ; Viossat, Y. ; Noble, R.
Preventing evolutionary rescue in cancer using two-strike therapy.
Genetics nn, nn (2025) [10.1093/genetics/iyaf255]2025
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Journal Article
Shang, F. (First author)DKFZ* ; Nizharadze, T.DKFZ* ; Thiele, R.DKFZ* ; Cirovic, B.DKFZ* ; Frank, L. J.DKFZ* ; Busch, K.DKFZ* ; Pei, W. ; Feyerabend, T.DKFZ* ; Höfer, T.DKFZ* ; Wang, X. ; Rodewald, H.-R. (Last author)DKFZ*
Multipotent progenitors with distinct origins, clonal lineage fates, transcriptomes, and surface markers yield two hematopoietic trees.
Proceedings of the National Academy of Sciences of the United States of America 122(48), e2505510122 (2025) [10.1073/pnas.2505510122]2025
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Journal Article (Erratum/Correction)
Smirnov, P. (First author)DKFZ* ; Przybilla, M. J. (First author)DKFZ* ; Simovic-Lorenz, M. (First author)DKFZ* ; Parra, R. G. (First author)DKFZ* ; Susak, H. (First author)DKFZ* ; Aichmüller-Ratnaparkhe, M.DKFZ* ; Wong, J. K.DKFZ* ; Körber, V.DKFZ* ; Mallm, J.-P.DKFZ* ; Philippos, G.DKFZ* ; Sill, M.DKFZ* ; Kolb, T.DKFZ* ; Kumar, R.DKFZ* ; Casiraghi, N.DKFZ* ; Okonechnikov, K.DKFZ* ; Ghasemi, D. R.DKFZ* ; Maaß, K. K.DKFZ* ; Pajtler, K.DKFZ* ; Jauch, A. ; Korshunov, A.DKFZ* ; Höfer, T.DKFZ* ; Zapatka, M.DKFZ* ; Pfister, S.DKFZ* ; Huber, W.DKFZ* ; Stegle, O. (Last author)DKFZ* ; Ernst, A. (Last author)DKFZ*
Author Correction: Multi-omic and single-cell profiling of chromothriptic medulloblastoma reveals genomic and transcriptomic consequences of genome instability.
Nature Communications 16(1), 1085 (2025) [10.1038/s41467-025-56164-7]2025
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Journal Article
Günther, M. (First author)DKFZ* ; Sticht, J. ; Freund, C. ; Höfer, T. (Last author)DKFZ*
Antigen presentation by MHC-II is shaped by competitive and cooperative allosteric mechanisms of peptide exchange.
Structure 33(2), 389-400.e13 (2025) [10.1016/j.str.2024.11.014]2025
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Preprint
Köberer, N. (First author)DKFZ* ; Jakobsen, N. A. ; Ansari-Pour, N. ; Moore, R. ; Claudino, N.DKFZ* ; Marlen, M. ; Thielecke, E.DKFZ* ; Hörsch, F.DKFZ* ; Salazar, M. A. ; Usukhbaya, B. ; simon, N. ; Kendrick, B. J. ; Taylor, A. H. ; Afinowi-Luitz, R. ; Gundle, R. ; Watkins, B. ; Wheway, K. ; Beazley, D. ; Dakin, S. G. ; Carr, A. J. ; Vyas, P. (Corresponding author) ; Höfer, T. (Last author)DKFZ*
Detecting and quantifying clonal selection in somatic stem cells
Nature Genetics (2025) [DOI:10.1101/2021.12.15.472780 ]2025
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Preprint
Günther, M. (First author)DKFZ* ; Sticht, J. ; Freund, C. ; Höfer, T. (Last author)DKFZ*
Antigen presentation by MHC-II is shaped by competitive and cooperative allosteric mechanisms of peptide exchange
Fulltext
BibTeX |
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http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png
Preprint
Okonechnikov, K. (First author)DKFZ* ; Joshi, P. K.DKFZ* ; Körber, V.DKFZ* ; Rademacher, A.DKFZ* ; Bortolomeazzi, M.DKFZ* ; Mallm, J.-P.DKFZ* ; da Silva, P. B. G.DKFZ* ; Statz, B.DKFZ* ; Sepp, M. ; Sarropoulos, I. ; Yamada-Saito, T. ; Vaillant, J.DKFZ* ; Wittmann, A.DKFZ* ; Schramm, K.DKFZ* ; Blattner-Johnson, M.DKFZ* ; Fiesel, P.DKFZ* ; Jones, B.DKFZ* ; Milde, T.DKFZ* ; Pajtler, K.DKFZ* ; van Tilburg, C. M.DKFZ* ; Witt, O.DKFZ* ; Bochennek, K. ; Weber, K. J. ; Nonnenmacher, L. ; Reimann, C. ; Schüller, U. ; Mynarek, M. ; Rutkowski, S. ; Jones, D. T. W.DKFZ* ; Korshunov, A.DKFZ* ; Rippe, K.DKFZ* ; Westermann, F.DKFZ* ; Thongjuea, S.DKFZ* ; Höfer, T.DKFZ* ; Kaessmann, H. ; Kutscher, L.DKFZ* ; Pfister, S. (Last author)DKFZ*
Medulloblastoma oncogene aberrations are not involved in tumor initiation, but essential for disease progression and therapy resistance
[doi.org/10.1101/2024.02.09.579690]
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All known publications ...
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