B260
Bioinformatik der Genomik und Systemgenetik
Also known as:B260 Bioinformatik der Genomik und Systemgenetik
| ID | I:(DE-He78)B260-20160331 |
Recent Publications
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Journal Article
Breinig, M. ; Lomakin, A. (First author)DKFZ* ; Heidari, E. (First author)DKFZ* ; Ritter, M.DKFZ* ; Rukhovich, G.DKFZ* ; Böse, L. ; Butthof, L. ; Wendler-Link, L. ; Wiethoff, H. ; Poth, T. ; Sahm, F.DKFZ* ; Schirmacher, P. ; Stegle, O.DKFZ* ; Gerstung, M.DKFZ* ; Tschaharganeh, D. F. (Last author)DKFZ*
Integrated in vivo combinatorial functional genomics and spatial transcriptomics of tumours to decode genotype-to-phenotype relationships.
Nature biomedical engineering 10(1), 125-143 (2026) [10.1038/s41551-025-01437-1]2026
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Journal Article
Hauth, A. ; Panten, J. (First author)DKFZ* ; Kneuss, E. ; Picard, C. ; Servant, N. ; Rall, I. ; Pérez-Rico, Y. A. ; Clerquin, L. ; Servaas, N. ; Villacorta, L. ; Jung, F. ; Luong, C. ; Chang, H. Y. ; Zaugg, J. B. ; Stegle, O.DKFZ* ; Odom, D.DKFZ* ; Heard, E. ; Loda, A.
Escape from X inactivation is directly modulated by Xist noncoding RNA.
Nature cell biology 28(1), 166-181 (2026) [10.1038/s41556-025-01823-6]2026
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Journal Article (Review Article)
Hartmann, M. (First author)DKFZ* ; Schönung, M. (First author)DKFZ* ; Rajak, J. ; Maurer, V.DKFZ* ; Hai, L.DKFZ* ; Bauer, K.DKFZ* ; Hakobyan, M.DKFZ* ; Stäble, S.DKFZ* ; Langstein, J.DKFZ* ; Jardine, L. ; Roelz, R. ; Bohler, S. ; Khabirova, E. ; Maag, A.-H. ; Vonficht, D.DKFZ* ; Lebrecht, D. ; Bernt, K. M. ; Tan, K. ; Chen, C. ; Alikarami, F. ; Meyer, J. ; Wang, J. ; Boch, T. ; Flore, N. V.DKFZ* ; Lutsik, P.DKFZ* ; Milsom, M.DKFZ* ; Raffel, S. ; Buske, C. ; Haas, S. ; Haniffa, M. ; Mallm, J.-P.DKFZ* ; Behjati, S. ; Bonder, M. J.DKFZ* ; Fröhling, S.DKFZ* ; Stieglitz, E. ; Niemeyer, C. M. ; Hey, J. (Last author)DKFZ* ; Flotho, C.DKFZ* ; Plass, C. (Last author)DKFZ* ; Erlacher, M.DKFZ* ; Schlesner, M. (Last author)DKFZ* ; Lipka, D. (Last author)DKFZ*
Molecular Plasticity Results in Oncofetal Reprogramming and Therapeutic Vulnerabilities in Juvenile Myelomonocytic Leukemia.
Blood cancer discovery 7(2), 306-330 (2026) [10.1158/2643-3230.BCD-25-0246]2026
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Journal Article
Feng, C. ; Peets, E. M. ; Zhou, Y. ; Crepaldi, L. ; Usluer, S. ; Dunham, A. ; Braunger, J. M. ; Su, J. ; Strauss, M. E. ; Muraro, D. ; Xian Cheam, K. A. ; Bonder, M. J.DKFZ* ; Nogales, E. G. ; Cooper, S. ; Bassett, A. ; Leonard, S. ; Gu, Y. ; Fussing, B. ; Burke, D. ; Parts, L. ; Stegle, O.DKFZ* ; Velten, B.
A genome-scale single-cell CRISPRi map of trans gene regulation across human pluripotent stem cell lines.
Cell genomics 6(2), 101076 (2026) [10.1016/j.xgen.2025.101076]2026
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Journal Article (Letter)
Koutrouli, M. ; Finotello, F. ; Schoof, E. M. ; Roussos, P. ; Vierdag, W.-M. ; Diedrich, L. ; Meyer-Bender, M. ; Kuehl, M. ; Nimo, J. ; Vöhringer, H. ; Visvikis, T. ; Brennsteiner, V. ; Marconato, L.DKFZ* ; Aragon-Fernandez, P. ; Petschko, F. ; Marco Salas, S. ; Leote, C. ; Rose, C. M. ; FNU, P. ; Hoffman, G. E. ; Heeren, R. M. A. ; Gaifas, L. ; Petrosius, V. ; Puelles, V. G. ; Cuypers, E. ; Mann, M. ; Coscia, F. ; Saka, S. K. ; Huber, W. ; Marioni, J. C. ; Theis, F. J.
Unpaired data as a first-order challenge in single-cell and spatial proteomics
Nature biotechnology nn, nn (2026) [10.1038/s41587-026-03074-8]2026
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Journal Article
Kersting, J. ; Lazareva, O.DKFZ* ; Louadi, Z. ; Baumbach, J. ; Blumenthal, D. B. ; List, M.
DysRegNet: Patient-specific and confounder-aware dysregulated network inference towards precision therapeutics.
British journal of pharmacology 183(8), 1709-1724 (2026) [10.1111/bph.17395]2026
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Journal Article
Riediger, A. L. (First author)DKFZ* ; Eickelschulte, S.DKFZ* ; Janke, F.DKFZ* ; Janscho, D.DKFZ* ; Lazareva, O.DKFZ* ; Hübschmann, D.DKFZ* ; Duensing, S. ; Stegle, O.DKFZ* ; Sültmann, H.DKFZ* ; Görtz, M. (Last author)DKFZ*
Multimodal plasma and urinary cell-free DNA profiling improves risk stratification in newly diagnosed prostate cancer.
npj precision oncology 10, 115 (2026) [10.1038/s41698-026-01343-y]2026
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Journal Article (Review Article)
Dimitrov, D. (First author)DKFZ* ; Schrod, S. (First author)DKFZ* ; Rohbeck, M.DKFZ* ; Stegle, O. (Last author)DKFZ*
Interpretation, extrapolation and perturbation of single cells.
Nature reviews / Genetics 27(5), 349–370 (2026) [10.1038/s41576-025-00920-4]2026
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Journal Article (Review Article)
Zulueta-Coarasa, T. ; Jug, F. ; Mathur, A. ; Moore, J. ; Muñoz-Barrutia, A. ; Anita, L. ; Babalola, K. ; Bankhead, P. ; Gilloteaux, P. ; Gogoberidze, N. ; Jones, M. L. ; Kleywegt, G. J. ; Korir, P. ; Kreshuk, A. ; Küpcü Yoldaş, A. ; Marconato, L.DKFZ* ; Narayan, K. ; Norlin, N. ; Oezdemir, B. ; Riesterer, J. L. ; Russell, C. ; Rzepka, N. ; Sarkans, U. ; Serrano-Solano, B. ; Tischer, C. ; Uhlmann, V. ; Ulman, V. ; Hartley, M.
MIFA: Metadata, Incentives, Formats and Accessibility guidelines to improve the reuse of AI datasets for bioimage analysis.
Nature methods 22(11), 2245-2252 (2025) [10.1038/s41592-025-02835-8]2025
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Journal Article
Lindenhofer, D. ; Bauman, J. R. ; Hawkins, J. A.DKFZ* ; Fitzgerald, D. ; Yildiz, U. ; Jung, H. ; Korosteleva, A. ; Marttinen, M. ; Kueblbeck, M. ; Zaugg, J. B. ; Noh, K.-M. ; Dietrich, S. ; Huber, W. ; Stegle, O.DKFZ* ; Steinmetz, L. M.
Functional phenotyping of genomic variants using joint multiomic single-cell DNA-RNA sequencing.
Nature methods 22(10), 2032-2041 (2025) [10.1038/s41592-025-02805-0]2025
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All known publications ...
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