B260
Bioinformatik der Genomik und Systemgenetik
Also known as:B260 Bioinformatik der Genomik und Systemgenetik
| ID | I:(DE-He78)B260-20160331 |
Recent Publications
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Preprint
Ishaque, N. ; Kharchenko, P. ; Lazic, D. ; Sun, J. ; Yang, J. Y. H. ; Emons, M. ; Heyl, F.DKFZ* ; Huber, W. ; Jones, D. ; Kuemmerle, L. B. ; Lederer, A. R. ; Luecken, M. D. ; Maracaja-Coutinho, V. ; Meyer-Bender, M. ; Moorman, A. ; Newell, E. W. ; Nguyen, Q. ; Prabhakar, S. ; Randell, J. ; Romanovskaia, D. ; Stegle, O.DKFZ* ; Bader, G. D. ; Gottardo, R.
The Challenge of Cell Segmentation in Spatially Resolved Transcriptomics
[doi.org/10.48550/arXiv.2606.09675]
Fulltext by arXiv.org
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Preprint
Moeed, A.DKFZ* ; Schrod, S.DKFZ* ; Rohbeck, M.DKFZ* ; Bonder, M. J. ; Lutsik, P. ; Stegle, O.DKFZ* ; Dimitrov, D.DKFZ*
Querying Counterfactuals on Tissue Graphs with Supervised Disentanglement
[doi.org/10.48550/arXiv.2606.08493]
Fulltext by arXiv.org
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Journal Article
Breinig, M. ; Lomakin, A. (First author)DKFZ* ; Heidari, E. (First author)DKFZ* ; Ritter, M.DKFZ* ; Rukhovich, G.DKFZ* ; Böse, L. ; Butthof, L. ; Wendler-Link, L. ; Wiethoff, H. ; Poth, T. ; Sahm, F.DKFZ* ; Schirmacher, P. ; Stegle, O.DKFZ* ; Gerstung, M.DKFZ* ; Tschaharganeh, D. F. (Last author)DKFZ*
Integrated in vivo combinatorial functional genomics and spatial transcriptomics of tumours to decode genotype-to-phenotype relationships.
Nature biomedical engineering 10(1), 125-143 (2026) [10.1038/s41551-025-01437-1]2026
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Journal Article
Masika, H. ; Ruppo, S. ; Clark, S. J. ; Bonder, M. J.DKFZ* ; von Meyenn, F. ; Hecht, M. ; Orlanski, S. ; Katsman, E. ; Vardi-Yaakov, O. ; Zlotogorski, A. ; Fachler-Sharp, T. ; Elgavish, S. ; Dor, Y. ; Reik, W. ; Kaplan, T. ; Cedar, H.
Cell-to-cell variability and gain of methylation at polycomb CpG islands as a hallmark of aging.
Nature Communications 17(1), 7318 (2026) [10.1038/s41467-026-74118-5]2026
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Journal Article
Hauth, A. ; Panten, J. (First author)DKFZ* ; Kneuss, E. ; Picard, C. ; Servant, N. ; Rall, I. ; Pérez-Rico, Y. A. ; Clerquin, L. ; Servaas, N. ; Villacorta, L. ; Jung, F. ; Luong, C. ; Chang, H. Y. ; Zaugg, J. B. ; Stegle, O.DKFZ* ; Odom, D.DKFZ* ; Heard, E. ; Loda, A.
Escape from X inactivation is directly modulated by Xist noncoding RNA.
Nature cell biology 28(1), 166-181 (2026) [10.1038/s41556-025-01823-6]2026
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Journal Article (Review Article)
Hartmann, M. (First author)DKFZ* ; Schönung, M. (First author)DKFZ* ; Rajak, J. ; Maurer, V.DKFZ* ; Hai, L.DKFZ* ; Bauer, K.DKFZ* ; Hakobyan, M.DKFZ* ; Stäble, S.DKFZ* ; Langstein, J.DKFZ* ; Jardine, L. ; Roelz, R. ; Bohler, S. ; Khabirova, E. ; Maag, A.-H. ; Vonficht, D.DKFZ* ; Lebrecht, D. ; Bernt, K. M. ; Tan, K. ; Chen, C. ; Alikarami, F. ; Meyer, J. ; Wang, J. ; Boch, T. ; Flore, N. V.DKFZ* ; Lutsik, P.DKFZ* ; Milsom, M.DKFZ* ; Raffel, S. ; Buske, C. ; Haas, S. ; Haniffa, M. ; Mallm, J.-P.DKFZ* ; Behjati, S. ; Bonder, M. J.DKFZ* ; Fröhling, S.DKFZ* ; Stieglitz, E. ; Niemeyer, C. M. ; Hey, J. (Last author)DKFZ* ; Flotho, C.DKFZ* ; Plass, C. (Last author)DKFZ* ; Erlacher, M.DKFZ* ; Schlesner, M. (Last author)DKFZ* ; Lipka, D. (Last author)DKFZ*
Molecular Plasticity Results in Oncofetal Reprogramming and Therapeutic Vulnerabilities in Juvenile Myelomonocytic Leukemia.
Blood cancer discovery 7(2), 306-330 (2026) [10.1158/2643-3230.BCD-25-0246]2026
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Journal Article
Feng, C. ; Peets, E. M. ; Zhou, Y. ; Crepaldi, L. ; Usluer, S. ; Dunham, A. ; Braunger, J. M. ; Su, J. ; Strauss, M. E. ; Muraro, D. ; Xian Cheam, K. A. ; Bonder, M. J.DKFZ* ; Nogales, E. G. ; Cooper, S. ; Bassett, A. ; Leonard, S. ; Gu, Y. ; Fussing, B. ; Burke, D. ; Parts, L. ; Stegle, O.DKFZ* ; Velten, B.
A genome-scale single-cell CRISPRi map of trans gene regulation across human pluripotent stem cell lines.
Cell genomics 6(2), 101076 (2026) [10.1016/j.xgen.2025.101076]2026
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Journal Article (Letter)
Koutrouli, M. ; Finotello, F. ; Schoof, E. M. ; Roussos, P. ; Vierdag, W.-M. ; Diedrich, L. ; Meyer-Bender, M. ; Kuehl, M. ; Nimo, J. ; Vöhringer, H. ; Visvikis, T. ; Brennsteiner, V. ; Marconato, L.DKFZ* ; Aragon-Fernandez, P. ; Petschko, F. ; Marco Salas, S. ; Leote, C. ; Rose, C. M. ; FNU, P. ; Hoffman, G. E. ; Heeren, R. M. A. ; Gaifas, L. ; Petrosius, V. ; Puelles, V. G. ; Cuypers, E. ; Mann, M. ; Coscia, F. ; Saka, S. K. ; Huber, W. ; Marioni, J. C. ; Theis, F. J.
Unpaired data as a first-order challenge in single-cell and spatial proteomics
Nature biotechnology 44, 891–892 (2026) [10.1038/s41587-026-03074-8]2026
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Journal Article
Kersting, J. ; Lazareva, O.DKFZ* ; Louadi, Z. ; Baumbach, J. ; Blumenthal, D. B. ; List, M.
DysRegNet: Patient-specific and confounder-aware dysregulated network inference towards precision therapeutics.
British journal of pharmacology 183(8), 1709-1724 (2026) [10.1111/bph.17395]2026
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Journal Article
Riediger, A. L. (First author)DKFZ* ; Eickelschulte, S.DKFZ* ; Janke, F.DKFZ* ; Janscho, D.DKFZ* ; Lazareva, O.DKFZ* ; Hübschmann, D.DKFZ* ; Duensing, S. ; Stegle, O.DKFZ* ; Sültmann, H.DKFZ* ; Görtz, M. (Last author)DKFZ*
Multimodal plasma and urinary cell-free DNA profiling improves risk stratification in newly diagnosed prostate cancer.
npj precision oncology 10, 115 (2026) [10.1038/s41698-026-01343-y]2026
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All known publications ...
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