W015
Innovations- und Service-Unit für Bioinformatik und Präzisionsmedizin
| ID | I:(DE-He78)W015-20160331 |
Recent Publications
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Journal Article
Czernilofsky, F. ; Mathioudaki, A. (First author)DKFZ* ; Jopp-Saile, L. (First author)DKFZ* ; Lutz, R.DKFZ* ; Vonficht, D.DKFZ* ; Wang, X. ; Schniederjohann, C. ; Voehringer, H. ; Roider, T. ; Baertsch, M.-A. ; Rodemer, C. ; Löffler-Wirth, H. ; Grau, M. ; Fitzgerald, D. ; Mammen, J. ; Kosla, J.DKFZ* ; Liebers, N. ; Bruch, P.-M. ; Ordoñez-Rueda, D. ; Brobeil, A. ; Mechtersheimer, G. ; Pabst, C. ; Müller-Tidow, C. ; Trumpp, A.DKFZ* ; Seifert, M. ; Neumann, F. ; Heikenwälder, M.DKFZ* ; Benes, V. ; Huber, W. ; Distler, J. ; Lenz, G. ; Binder, H. ; Siebert, R. ; Nolan, G. P. ; Gerstung, M.DKFZ* ; Zaugg, J. B. ; Hübschmann, D. (Last author)DKFZ* ; Haas, S.DKFZ* ; Dietrich, S.
Reprogramming of stroma-derived chemokine networks drives the loss of tissue organization in nodal B cell lymphoma.
Nature cancer 7(3), 538-552 (2026) [10.1038/s43018-026-01136-z]2026
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Rodríguez-Correa, E. (First author)DKFZ* ; Grünschläger, F. (First author)DKFZ* ; Nizharadze, T. (First author)DKFZ* ; Anstee, N. S.DKFZ* ; Al-Sabah, J.DKFZ* ; Kumpost, V. ; Sedlmeier, A.DKFZ* ; Li, C.DKFZ* ; Ball, M.DKFZ* ; Fotopoulou, F.DKFZ* ; Jayarajan, J.DKFZ* ; Ghezzi, I.DKFZ* ; Knoch, J.DKFZ* ; Druce, M. C.DKFZ* ; Aurich, K.DKFZ* ; Büchler-Schäff, M.DKFZ* ; Lux, S.DKFZ* ; Hernández-Malmierca, P.DKFZ* ; Gräsel, J.DKFZ* ; Vonficht, D.DKFZ* ; López-Osias, M. ; González-Saiz, E. ; Fernández-Pérez, D. ; Mathioudaki, A.DKFZ* ; Zaugg, J. ; Rodríguez-Fraticelli, A. ; Mikut, R. ; Trumpp, A.DKFZ* ; Höfer, T.DKFZ* ; Hübschmann, D.DKFZ* ; Haas, S. ; Milsom, M. (Last author)DKFZ*
A kinetics-based model of haematopoiesis reveals extrinsic regulation of skewed lineage output from stem cells.
Nature cell biology 28(6), 1127-1140 (2026) [10.1038/s41556-026-01958-0]2026
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Triebig, A. S. ; Maier, T. ; Schwarzlmueller, P. ; Atici, S. ; Kirmaier, M. E. ; Chortis, V. ; Borges, K. S. ; Breault, D. T. ; Ribeiro, C. ; Gottschlich, A.DKFZ* ; Landwehr, L.-S. ; Bechmann, N. ; Peitzsch, M. ; Paramasivam, N. ; Theurich, S. ; Fröhling, S.DKFZ* ; Glimm, H.DKFZ* ; Hübschmann, D.DKFZ* ; Fassnacht, M. ; Reincke, M. ; Friedmann-Angeli, J. P. ; Weigand, I. ; Kroiss, M.
Glucocorticoids induce a phagocytic C1Q+ macrophage phenotype primed for IFNγ-dependent CXCL9 secretion.
Scientific reports 16(1), 15345 (2026) [10.1038/s41598-026-52733-y]2026
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Journal Article
Renner, M. (First author)DKFZ* ; Oleś, M. ; Paramasivam, N. ; Heilig, C.DKFZ* ; Schneider, A.DKFZ* ; Modugno, C. ; Herremans, C. ; Hüllein, J. ; Hutter, B. ; Erkut, C.DKFZ* ; Mock, A.DKFZ* ; Krieghoff-Henning, E.DKFZ* ; Jensen, C. B. ; Sakhteman, A. ; The, M. ; Prinz, T.DKFZ* ; Lajer, P.DKFZ* ; Baude-Müller, A.DKFZ* ; Beck, K.DKFZ* ; Beuthien-Baumann, B.DKFZ* ; Apostolidis, L. ; Bauer, S.DKFZ* ; Boerries, M.DKFZ* ; Brandts, C. H.DKFZ* ; Rieke, D.DKFZ* ; Kindler, T.DKFZ* ; Klauschen, F.DKFZ* ; Schulze-Osthoff, K.DKFZ* ; Schlenk, R.DKFZ* ; Berchem, G. ; Allgäuer, M. ; Mechtersheimer, G. ; Stenzinger, A. ; Lipka, D.DKFZ* ; Schlesner, M. ; Kuster, B.DKFZ* ; Jahn, A.DKFZ* ; Schröck, E.DKFZ* ; Heining, C.DKFZ* ; Teleanu, M.-V.DKFZ* ; Horak, P.DKFZ* ; Kreutzfeldt, S.DKFZ* ; Hübschmann, D.DKFZ* ; Hartmann, W. ; Glimm, H.DKFZ* ; Fröhling, S. (Last author)DKFZ*
Multi-layered molecular profiling informs the diagnosis and targeted therapy of desmoplastic small round cell tumor.
Nature Communications 17(1), 3397 (2026) [10.1038/s41467-026-71636-0]2026
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Journal Article
Merkt, W. ; Rodon, L. ; Deicher, F. S. ; Freitag, M. ; Claus, M. ; Lister, R. ; Han, H. ; Zhou, Y. ; Horne, A.DKFZ* ; Stütz, A. ; Li, Y.-N. ; Kreuter, M. ; Kahn, N. ; Schneider, M. A. ; Egea-Zorrilla, A. ; Blasco-Iturri, Z. ; Nikulina, N. ; Turkowski, K. ; Ruppert, C. ; Guenther, A. ; Rizzo, R. ; Rizzo, S. ; Ferraresi, M. ; Hübschmann, D.DKFZ* ; Haas, S. ; Blank, N. ; Watzl, C. ; Tykocinski, L.-O. ; Lorenz, H.-M. ; Savai, R. ; Pardo-Saganta, A. ; Lagares, D.
Natural killer cell immunotherapy reverses lung fibrosis by eliminating senescent fibroblasts.
Science translational medicine 18(849), eadq5442 (2026) [10.1126/scitranslmed.adq5442]2026
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Journal Article
Nichetti, F.DKFZ* ; Hoffmeister, P.DKFZ* ; Korell, F. ; Hüllein, J.DKFZ* ; Uhrig, S.DKFZ* ; Rübsam, M.DKFZ* ; Schwab, M.DKFZ* ; Teleanu, M.-V.DKFZ* ; Jenzer, M.DKFZ* ; Kreutzfeld, S.DKFZ* ; Horak, P.DKFZ* ; Konietzke, P. ; Glimm, H.DKFZ* ; Heining, C.DKFZ* ; Rieke, D. ; Kindler, T. ; Springfeld, C.DKFZ* ; Heilig, C. E.DKFZ* ; Hübschmann, D.DKFZ* ; Fröhling, S. ; Köhler, B. C.DKFZ*
Deep molecular profiling of biliary tract cancer uncovers novel biological mechanisms and therapeutic opportunities.
ESMO open 11(5), 106082 (2026) [10.1016/j.esmoop.2026.106082]2026
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Journal Article
Kreutzfeldt, S. (First author)DKFZ* ; Apostolidis, L.DKFZ* ; Oleś, M. ; Krieghoff-Henning, E.DKFZ* ; Heilig, C.DKFZ* ; Heining, C.DKFZ* ; Mock, A.DKFZ* ; Teleanu, M.-V.DKFZ* ; Hutter, B.DKFZ* ; Gieldon, L. ; Klink, B. ; Beck, K.DKFZ* ; Richter, D.DKFZ* ; Baude-Müller, A.DKFZ* ; Reisinger, E.-M.DKFZ* ; Hammer, N.DKFZ* ; Kamkar, L.DKFZ* ; Pfütze, K.DKFZ* ; Geörg, C.DKFZ* ; Lamping, M.DKFZ* ; Rieke, D.DKFZ* ; Uhrig, S.DKFZ* ; Jann, H. ; Pape, U.-F. ; Allgäuer, M. ; Stenzinger, A. ; Winkler, E.DKFZ* ; Wiedenmann, B. ; Jäger, D.DKFZ* ; Brors, B.DKFZ* ; Hübschmann, D.DKFZ* ; Schröck, E.DKFZ* ; Keilholz, U.DKFZ* ; Pavel, M. ; Horak, P.DKFZ* ; Glimm, H.DKFZ* ; Fröhling, S.DKFZ*
Clinically actionable genomic and transcriptomic landscape of advanced neuroendocrine neoplasms.
Med 7(6), 101130 (2026) [10.1016/j.medj.2026.101130]2026
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Journal Article
Nichetti, F. (First author)DKFZ* ; Hüllein, J. (First author)DKFZ* ; du Rusquec, P. ; Pleasance, E. ; Chen, L. ; Mock, A. ; Horak, P.DKFZ* ; Ambrosini, P. ; Rota, S. ; Niger, M. ; Agnelli, L. ; Tinè, G. ; Edelmann, D.DKFZ* ; Le Tourneau, C. ; Laskin, J. ; Pruneri, G. ; Wang, C. ; Hübschmann, D.DKFZ* ; de Braud, F. ; Fröhling, S. (Last author)DKFZ* ; Mariani, L.
Benchmarking progression-free survival ratio as primary endpoint in precision oncology clinical trials.
npj precision oncology 10, 38 (2026) [10.1038/s41698-025-01231-x]2026
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Journal Article
Riediger, A. L. (First author)DKFZ* ; Eickelschulte, S.DKFZ* ; Janke, F.DKFZ* ; Janscho, D.DKFZ* ; Lazareva, O.DKFZ* ; Hübschmann, D.DKFZ* ; Duensing, S. ; Stegle, O.DKFZ* ; Sültmann, H.DKFZ* ; Görtz, M. (Last author)DKFZ*
Multimodal plasma and urinary cell-free DNA profiling improves risk stratification in newly diagnosed prostate cancer.
npj precision oncology 10, 115 (2026) [10.1038/s41698-026-01343-y]2026
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Journal Article
Hübschmann, D. (First author)DKFZ* ; Kreutzfeldt, S. (First author)DKFZ* ; Roth, B. (First author)DKFZ* ; Glocker, K. (First author)DKFZ* ; Schoop, J.DKFZ* ; Oeser, L.DKFZ* ; Hausmann, S.DKFZ* ; Koch, C.DKFZ* ; Uhrig, S.DKFZ* ; Hüllein, J.DKFZ* ; Hutter, B.DKFZ* ; Fröhlich, M. A.DKFZ* ; Heilig, C.DKFZ* ; Teleanu, M.-V.DKFZ* ; Lipka, D.DKFZ* ; Kerle, I.DKFZ* ; Baude-Müller, A.DKFZ* ; Beck, K.DKFZ* ; Heining, C.DKFZ* ; Glimm, H.DKFZ* ; Ückert, F. ; Knurr, A. (Last author)DKFZ* ; Fröhling, S. (Last author)DKFZ* ; Horak, P. (Last author)DKFZ*
The Knowledge Connector decision support system for multiomics-based precision oncology.
Nature Communications 17(1), 742 (2026) [10.1038/s41467-026-68333-3]2026
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All known publications ...
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