W015
Innovations- und Service-Unit für Bioinformatik und Präzisionsmedizin
ID | I:(DE-He78)W015-20160331 |
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Heilig, C. (First author)DKFZ* ; Heining, C.DKFZ* ; Gnutzmann, E.DKFZ* ; Roldan, S. ; Heiligenthal, L.DKFZ* ; Sparber-Sauer, M. ; Hahn, D. ; Dirksen, U. ; Hamacher, R.DKFZ* ; Flörcken, A. ; Thorwarth, A. ; Deinzer, C. K. W. ; Gaidzik, V. I. ; Pfaff, E.DKFZ* ; Hübschmann, D.DKFZ* ; Arndt, K. ; Pfister, S. M.DKFZ* ; Glimm, H.DKFZ* ; Fröhling, S.DKFZ* ; Schlenk, R. (Last author)DKFZ*
Rationale and design of the PAMSARC (pasireotide as maintenance treatment with monthly deep intramuscular injection in SSTR2/3/5-expressing synovial sarcoma and desmoplastic small round cell tumor) multicenter phase 2 trial.
Cancer treatment and research communications 45, 100986 (2025) [10.1016/j.ctarc.2025.100986]2025
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Lange, S. ; Lisiecki, H. ; Kreutzfeldt, S.DKFZ* ; Heining, C.DKFZ* ; Weiss, L. ; Westphalen, C. B.DKFZ* ; Stenzinger, A. ; Hübschmann, D.DKFZ* ; Jesinghaus, M. ; Glimm, H.DKFZ* ; Fröhling, S.DKFZ* ; Pfarr, N. ; Schlitter, A. M.DKFZ*
Precision oncology for advanced-stage adenocarcinoma of the appendix: comprehensive molecular characterisation identifies actionable lesions and potential predictive biomarkers.
BMJ open gastroenterology 12(1), e001671 (2025) [10.1136/bmjgast-2024-001671]2025
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William, D.DKFZ* ; Bermúdez, M.DKFZ* ; Kübler, A.DKFZ* ; et al
17.6% of patients in a German cohort with exocrine pancreatic cancer were diagnosed with a genetic tumor syndrome—a case for universal genetic testing?
ESMO gastrointestinal oncology 9, 100218 (2025) [10.1016/j.esmogo.2025.100218]2025
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Vonficht, D. (First author)DKFZ* ; Jopp-Saile, L. (First author)DKFZ* ; Yousefian, S. ; Flore, V. ; Simó Vesperinas, I. ; Teuber, R. ; Avanesyan, B. ; Luo, Y. ; Röthemeier, C. ; Grünschläger, F.DKFZ* ; Fernandez-Vaquero, M.DKFZ* ; Fregona, V. ; Ordoñez-Rueda, D. ; Schmalbrock, L. K.DKFZ* ; Deininger, L. ; Yamachui Sitcheu, A. J. ; Gu, Z. ; Funk, M. C. ; Mikut, R. ; Heikenwälder, M.DKFZ* ; Eggert, A.DKFZ* ; von Stackelberg, A. ; Kobold, S.DKFZ* ; Krönke, J.DKFZ* ; Keller, U.DKFZ* ; Trumpp, A.DKFZ* ; Hegazy, A. N. ; Eckert, C. ; Hübschmann, D.DKFZ* ; Haas, S. (Last author)DKFZ*
Ultra-high-scale cytometry-based cellular interaction mapping.
Nature methods nn, nn (2025) [10.1038/s41592-025-02744-w]2025
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Sedda, F. ; Caddeo, A. ; Sasidharan, K. ; Perra, G. ; Pal, R.DKFZ* ; Lai, N. ; Kowalik, M. A. ; Perra, A.
Galectin-3 inhibition ameliorates hepatic steatosis in a multilineage 3D spheroid model.
PLOS ONE 20(7), e0326373 - (2025) [10.1371/journal.pone.0326373]2025
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Machiraju, D. ; Ziener, C. H.DKFZ* ; Clementi, E. ; García-Asencio, F. ; Hüllein, J.DKFZ* ; Richter, J. ; Lenoir, B. ; Wiecken, M. ; Hübschmann, D.DKFZ* ; Jäger, D.DKFZ* ; Hassel, J. C.
Monitoring soluble cMET and ctDNA in metastatic uveal melanoma patients to track early disease progression on immunotherapies.
Journal of experimental & clinical cancer research 44(1), 213 (2025) [10.1186/s13046-025-03451-2]2025
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Teleanu, M.-V. (First author)DKFZ* ; Heilig, C.DKFZ* ; Pirmann, S. ; Hamacher, R.DKFZ* ; Bauer, S.DKFZ* ; Gaidzik, V. I. ; Mayer-Steinacker, R. ; Al-Sabah, J. ; Roldan Pinzon, S. S. L. ; Süße, H. ; Freitag, A. ; Horak, P.DKFZ* ; Kreutzfeldt, S.DKFZ* ; Hutter, B. ; Hüllein, J. ; Sedlaczek, O.DKFZ* ; Lehner, B. ; Egerer, G. ; Jäger, D. ; Müller-Tidow, C. ; Hübschmann, D.DKFZ* ; von Kalle, C. ; Barth, T. F. E. ; Fröhling, S. (Last author)DKFZ* ; Schlenk, R. F.
CDK4/6 inhibition in advanced chordoma: final results of the NCT PMO-1601 trial.
ESMO open 10(7), 105498 (2025) [10.1016/j.esmoop.2025.105498]2025
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Gehrs, S. (First author)DKFZ* ; Gu, Z. ; Hey, J.DKFZ* ; Weichenhan, D.DKFZ* ; Buckwalter, N.DKFZ* ; Jakab, M. V.DKFZ* ; Hotz-Wagenblatt, A.DKFZ* ; Breuer, K.DKFZ* ; Prada, M. L.DKFZ* ; Hübschmann, D.DKFZ* ; Schlereth, K.DKFZ* ; Plass, C. (Last author)DKFZ* ; Augustin, H. (Last author)DKFZ*
DNMT3A-dependent DNA methylation shapes the endothelial enhancer landscape.
Nucleic acids research 53(10), gkaf435 (2025) [10.1093/nar/gkaf435]2025
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Möhrmann, L.DKFZ* ; Werner, M.DKFZ* ; Oles, M. (First author)DKFZ* ; Knol, L.DKFZ* ; Arnold, J.DKFZ* ; Mundt, T.DKFZ* ; Paramasivam, N.DKFZ* ; Richter, D.DKFZ* ; Fröhlich, M. A.DKFZ* ; Hutter, B.DKFZ* ; Hüllein, J.DKFZ* ; Jahn, A.DKFZ* ; Scheffold, C.DKFZ* ; Möhrmann, E. E.DKFZ* ; Hanf, D.DKFZ* ; Kreutzfeldt, S.DKFZ* ; Heilig, C.DKFZ* ; Teleanu, M.-V.DKFZ* ; Lipka, D.DKFZ* ; Beck, K.DKFZ* ; Baude-Müller, A.DKFZ* ; Jelas, I. ; Rieke, D. T. ; Klotz, L. V. ; Shah, R. ; Herold, T. ; Boerries, M. ; Illert, A. L. ; Allgäuer, M. ; Stenzinger, A. ; Kerle, I.DKFZ* ; Horak, P.DKFZ* ; Heining, C.DKFZ* ; Schröck, E.DKFZ* ; Hübschmann, D.DKFZ* ; Fröhling, S. (Last author)DKFZ* ; Glimm, H. (Last author)DKFZ*
Comprehensive genomic and transcriptomic analysis enables molecularly guided therapy options in peritoneal and pleural mesothelioma.
ESMO open 10(4), 104532 (2025) [10.1016/j.esmoop.2025.104532]2025
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Journal Article
Möhrmann, L.DKFZ* ; Rostock, L. ; Werner, M.DKFZ* ; Oleś, M.DKFZ* ; Arnold, J.DKFZ* ; Paramasivam, N.DKFZ* ; Jöhrens, K. ; Rupp, L. ; Schmitz, M. ; Richter, D. ; Uhrig, S.DKFZ* ; Fröhlich, M. A.DKFZ* ; Hutter, B.DKFZ* ; Hüllein, J.DKFZ* ; Jahn, A.DKFZ* ; Arlt, M.DKFZ* ; Möhrmann, E. E.DKFZ* ; Hanf, D.DKFZ* ; Gieldon, L. ; Kreutzfeldt, S.DKFZ* ; Heilig, C. E.DKFZ* ; Teleanu, M.-V.DKFZ* ; Lipka, D. B. ; Beck, K. ; Baude-Müller, A.DKFZ* ; Mock, A. ; Jelas, I. ; Rieke, D. T. ; Wiesweg, M. ; Brandts, C.DKFZ* ; Boerries, M. ; Illert, A. L. ; Desuki, A.DKFZ* ; Kindler, T.DKFZ* ; Krackhardt, A. M. ; Westphalen, C. B. ; Christopoulos, P. ; Apostolidis, L. ; Stenzinger, A. ; Allgäuer, M. ; Neumann, O. ; Kerle, I.DKFZ* ; Horak, P.DKFZ* ; Heining, C.DKFZ* ; Grosch, H. ; Schröck, E.DKFZ* ; Hübschmann, D. (Last author)DKFZ* ; Fröhling, S. (Last author)DKFZ* ; Glimm, H. (Last author)
Genomic landscape and molecularly informed therapy in thymic carcinoma and other advanced thymic epithelial tumors.
Med 6(6), 100612 (2025) [10.1016/j.medj.2025.100612]2025
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All known publications ...
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