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000294421 020__ $$a978-1-0716-1019-0 (print)
000294421 020__ $$a978-1-0716-1020-6 (electronic)
000294421 0247_ $$2doi$$a10.1007/978-1-0716-1020-6_18
000294421 0247_ $$2ISSN$$a1064-3745
000294421 0247_ $$2ISSN$$a1940-6029
000294421 037__ $$aDKFZ-2024-02250
000294421 041__ $$aEnglish
000294421 082__ $$a570
000294421 1001_ $$aCidre-Aranaz, Florencia$$b0$$eEditor
000294421 245__ $$aEwing Sarcoma PDX Models
000294421 260__ $$aNew York, NY$$bSpringer US$$c2021
000294421 29510 $$aEwing Sarcoma / Cidre-Aranaz, Florencia (Editor) ; New York, NY : Springer US, 2021, Chapter 18 ; ISSN: 1064-3745=1940-6029 ; ISBN: 978-1-0716-1019-0=978-1-0716-1020-6 ; doi:10.1007/978-1-0716-1020-6
000294421 300__ $$a223 - 242
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000294421 3367_ $$0PUB:(DE-HGF)7$$2PUB:(DE-HGF)$$aContribution to a book$$bcontb$$mcontb$$s1730991248_25139
000294421 4900_ $$aMethods in Molecular Biology$$v2226
000294421 520__ $$aEwing sarcoma (EWS) is a rare malignant pediatric tumor and patient derived xenografts (PDXs) could represent a possibility to increase the number of available models to study this disease. Compared to cell derived xenografts (CDX), PDXs are reported to better recapitulate tumor microenvironment, heterogeneity, genetic and epigenetic features and are considered reliable models for their better predictive value when comparing preclinical efficacy and treatment response in patients. In this chapter, we extensively describe a method for generating Ewing sarcoma PDX models, for their validation and molecular characterization.
000294421 588__ $$aDataset connected to CrossRef Book Series, Journals: inrepo02.dkfz.de
000294421 7001_ $$aG. P. Grünewald, Thomas$$b1$$eEditor
000294421 7001_ $$aSurdez, Didier$$b2
000294421 7001_ $$aLanduzzi, Lorena$$b3
000294421 7001_ $$aScotlandi, Katia$$b4
000294421 7001_ $$aManara, Maria Cristina$$b5
000294421 773__ $$a10.1007/978-1-0716-1020-6_18
000294421 8564_ $$uhttps://inrepo02.dkfz.de/record/294421/files/Surdez%20et%20al%20Methods%20in%20Molecular%20Biology%202020.pdf
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