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@INBOOK{CidreAranaz:294421,
      author       = {D. Surdez and L. Landuzzi and K. Scotlandi and M. C.
                      Manara},
      editor       = {F. Cidre-Aranaz and T. G. P. Grünewald},
      title        = {{E}wing {S}arcoma {PDX} {M}odels},
      volume       = {2226},
      address      = {New York, NY},
      publisher    = {Springer US},
      reportid     = {DKFZ-2024-02250},
      isbn         = {978-1-0716-1019-0 (print)},
      series       = {Methods in Molecular Biology},
      pages        = {223 - 242},
      year         = {2021},
      comment      = {Ewing Sarcoma / Cidre-Aranaz, Florencia (Editor) ; New
                      York, NY : Springer US, 2021, Chapter 18 ; ISSN:
                      1064-3745=1940-6029 ; ISBN:
                      978-1-0716-1019-0=978-1-0716-1020-6 ;
                      doi:10.1007/978-1-0716-1020-6},
      booktitle     = {Ewing Sarcoma / Cidre-Aranaz,
                       Florencia (Editor) ; New York, NY :
                       Springer US, 2021, Chapter 18 ; ISSN:
                       1064-3745=1940-6029 ; ISBN:
                       978-1-0716-1019-0=978-1-0716-1020-6 ;
                       doi:10.1007/978-1-0716-1020-6},
      abstract     = {Ewing sarcoma (EWS) is a rare malignant pediatric tumor and
                      patient derived xenografts (PDXs) could represent a
                      possibility to increase the number of available models to
                      study this disease. Compared to cell derived xenografts
                      (CDX), PDXs are reported to better recapitulate tumor
                      microenvironment, heterogeneity, genetic and epigenetic
                      features and are considered reliable models for their better
                      predictive value when comparing preclinical efficacy and
                      treatment response in patients. In this chapter, we
                      extensively describe a method for generating Ewing sarcoma
                      PDX models, for their validation and molecular
                      characterization.},
      ddc          = {570},
      typ          = {PUB:(DE-HGF)7},
      doi          = {10.1007/978-1-0716-1020-6_18},
      url          = {https://inrepo02.dkfz.de/record/294421},
}