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G404
WirkstoffforschungID | I:(DE-He78)G404-20160331 |
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Dissertation / PhD Thesis
Small Molecule KLK6 Inhibitors
Dissertation, Universität Heidelberg, 2018
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Depsipeptides Featuring a Neutral P1 Are Potent Inhibitors of Kallikrein-Related Peptidase 6 with On-Target Cellular Activity.
Journal of medicinal chemistry 61(19), 8859 - 8874 (2018) [10.1021/acs.jmedchem.8b01106]
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A potent, proteolysis-resistant inhibitor of kallikrein-related peptidase 6 (KLK6) for cancer therapy, developed by combinatorial engineering.
The journal of biological chemistry 293(33), 12663 - 12680 (2018) [10.1074/jbc.RA117.000871]
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Internal chirality descriptors iR and iS and ire and isi. A proposed notation to extend the usefulness of the R/S system by retaining the sense of stereochemistry in cases of ligand ranking changes.
Chirality 30(9), 1054 - 1066 (2018) [10.1002/chir.22982]
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Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance.
Scientific reports 8(1), 10039 (2018) [10.1038/s41598-018-28265-5]
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Characterization and Quantitation of Polyphenolic Compounds in Senna splendida from the Northeast of Brazil17
Natural product communications 13(6), 707 - 712 (2018)
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The HDAC6/8/10 inhibitor TH34 induces DNA damage-mediated cell death in human high-grade neuroblastoma cell lines.
Archives of toxicology 92(8), 2649 - 2664 (2018) [10.1007/s00204-018-2234-8]
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Parametric modeling and optimal experimental designs for estimating isobolograms for drug interactions in toxicology.
Journal of biopharmaceutical statistics 28(4), 763 - 777 (2018) [10.1080/10543406.2017.1397005]
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Reactive Oxygen Species Deficiency Due to Ncf1-Mutation Leads to Development of Adenocarcinoma and Metabolomic and Lipidomic Remodeling in a New Mouse Model of Dextran Sulfate Sodium-Induced Colitis
Frontiers in immunology 9, 701 (2018) [10.3389/fimmu.2018.00701]
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Carnosine Catalyzes the Formation of the Oligo/Polymeric Products of Methylglyoxal.
Cellular physiology and biochemistry 46(2), 713 - 726 (2018) [10.1159/000488727]
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