B110
Signalwege funktionelle Genomik
Also known as:B110 Signalwege funktionelle Genomik; Signalwege und Funktionelle Genomik
| ID | I:(DE-He78)B110-20160331 |
Recent Publications
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Iorio, F. ; Garnett, M. J. ; Beltrao, P. ; Billmann, M. ; Bless, L. ; Bock, C. ; Boutros, M.DKFZ* ; Bruna, A. ; Carninci, P. ; Ciriello, G. ; Cortés-Ciriano, I. ; D'Alessandro, G. ; Esposito, R. ; Faletti, S. ; Gonçalves, E. ; Haider, S. ; Kalebic, N. ; Kaulich, M. ; Leuzzi, G. ; Lopez-Bigas, N. ; Lord, C. J. ; Petsalaki, E. ; Pettitt, S. ; Proietti, L. ; Rad, R.DKFZ* ; Radic, N. ; Ryan, C. J. ; Schmid-Burgk, J. L. ; Sharma, S. ; Sottoriva, A. ; Tape, C. ; Trusolino, L. ; van Leeuwen, J. ; Walter, D. ; Wessels, L. ; consortium, P. (Collaboration Author)
The PRECISE European initiative for cancer-vulnerability mapping and prediction.
Nature genetics nn, nn (2026) [10.1038/s41588-026-02658-z]2026
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Redhai, S. (First author)DKFZ* ; Hirschmüller, N. ; Wang, T.DKFZ* ; Jackson, T. ; Peidli, S. ; Valentini, E.DKFZ* ; Bahuguna, S.DKFZ* ; Leible, S.DKFZ* ; Möller, S.DKFZ* ; Ko, C. ; Holzem, M.DKFZ* ; Kharuk, S. ; Bräckow, L.DKFZ* ; Port, F.DKFZ* ; Ibberson, D. ; Le, H. ; Huber, W. ; Boutros, M. (Last author)DKFZ*
Autoinhibitory feedback preserves intestinal stem cell maintenance and fate commitment.
The EMBO journal 45(13), 4636-4669 (2026) [10.1038/s44318-026-00808-x]2026
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Drozdowski, O. M. ; Kocameşe-Tamgac𝚤, B.DKFZ* ; Boonekamp, K. E.DKFZ* ; Boutros, M.DKFZ* ; Schwarz, U. S.
Cell Bulging and Extrusion in a Three-Dimensional Bubbly Vertex Model for Curved Epithelial Sheets
Physical review / X 16(2), 021023 (2026) [10.1103/x82g-cq7n]2026
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Venkatachalam, N. ; Wang, L. ; Muthukumarana, N. ; Ihnatko, R.DKFZ* ; Krijgsveld, J.DKFZ* ; Skabkina, O. ; Leipertz, A. ; Chen, Y. ; Sui, P.DKFZ* ; Zheng, Q. ; Tong, P. ; Liu, X. ; Descot, A. ; Schewe, M. ; Diamante, G.DKFZ* ; Jackstadt, R.DKFZ* ; Brochhausen, C. ; Betge, J.DKFZ* ; Boonekamp, K.DKFZ* ; Boutros, M.DKFZ* ; Stoecklin, G. ; Ebert, M. ; Schott, J. ; Zhan, T.
Ras-MAPK inhibition induces AXIN1 loss in colorectal cancer by mTOR associated suppression of protein synthesis.
Cell communication and signaling 24(1), 324 (2026) [10.1186/s12964-026-02963-4]2026
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Balzasch, B. M. ; von Kries, A. ; Hüll, S. ; Shaltiel, I. A. ; Boonekamp, K. E.DKFZ* ; Ast, V. ; Burgermeister, E. ; Betge, J.DKFZ* ; Ebert, M. ; Boutros, M.DKFZ* ; Helming, L. ; Umansky, V.DKFZ* ; Cerwenka, A.
Monocytes acquire a tumor-associated IL1B program upon encountering patient-derived colon cancer organoids.
OncoImmunology 15(1), 2633012 (2026) [10.1080/2162402X.2026.2633012]2026
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Boonekamp, K. E. (First author)DKFZ* ; Boutros, M. (Last author)DKFZ*
Primer: Drug discovery and patient-derived organoids
Current opinion in systems biology 44, 100579 (2026) [10.1016/j.coisb.2026.100579]2026
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Udayakumar, A. ; Stavropoulos, F. ; Hadjipanteli, T. ; Peng, G. ; Bahuguna, S.DKFZ* ; MacClay, C. ; Lee, J. Y. ; Xiao, Q. ; Xia, Y. ; Boutros, M.DKFZ* ; Zhou, J. ; Apidianakis, Y. ; Pitsouli, C. ; Ligoxygakis, P.
Toll signalling controls intestinal regeneration in Drosophila.
Development 153(2), dev204794 (2026) [10.1242/dev.204794]2026
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Port, F. J. (First author)DKFZ* ; Buhmann, M.DKFZ* ; Zhou, J.DKFZ* ; Stricker, M.DKFZ* ; Vaughan-Brown, A.DKFZ* ; Michalsen, A.-C.DKFZ* ; Roßmanith, E.DKFZ* ; Pöltl, A.DKFZ* ; Großkurth, L.DKFZ* ; Huber, J.DKFZ* ; Menendez Kury, L.DKFZ* ; Weberbauer, B.DKFZ* ; Hübl, M.DKFZ* ; Puscher, E.DKFZ* ; Heigwer, F.DKFZ* ; Boutros, M. (Last author)DKFZ*
Improved in vivo gene knockout with high specificity using multiplexed Cas12a sgRNAs.
Nature Communications 17(1), 877 (2026) [10.1038/s41467-026-68434-z]2026
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Lee, K. H. (First author)DKFZ* ; Jakab, M. V. (First author)DKFZ* ; Uvarovskii, A. ; Papageorgiou, D.DKFZ* ; Inverso, D.DKFZ* ; Shi, J.DKFZ* ; Riedel, M.DKFZ* ; Gehrs, S.DKFZ* ; Kulkarni, S.DKFZ* ; Bobe, S. ; Ali, A.DKFZ* ; Gallage, S. U.DKFZ* ; Siegmund, S. ; Gahn, J. ; Blankenhorn, L.DKFZ* ; Buettner, M. ; Poschet, G. ; Richter, K.DKFZ* ; Voloshanenko, O.DKFZ* ; Ola, R. ; Korff, T. ; Kiefer, F. ; Heikenwälder, M.DKFZ* ; Boutros, M.DKFZ* ; Niehrs, C.DKFZ* ; Mogler, C. ; Krijgsveld, J.DKFZ* ; Anders, S. ; Augustin, H. (Last author)DKFZ*
Haemodynamic control of zonated liver function via instructive vascular Wnt signalling.
Nature Communications 17(1), 8821 (2026) [10.1038/s41467-026-76966-7]2026
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Mastel, M. (First author)DKFZ* ; Guiseris Martinez, A.DKFZ* ; Pozza, U.DKFZ* ; Meier, J.DKFZ* ; Chiotakakos, I.DKFZ* ; Jaun, S.DKFZ* ; Artmann, C.DKFZ* ; Diamante, G.DKFZ* ; Georgakopoulos, N.DKFZ* ; Albrecht, P.DKFZ* ; Petersen, Y.DKFZ* ; Reuter, S.DKFZ* ; Schmitt, B.DKFZ* ; Günther, M. ; Thiran, A.DKFZ* ; Nurfauziah, I.DKFZ* ; Ghezzi, I.DKFZ* ; Ouyang, K. S.DKFZ* ; Milsom, M. D.DKFZ* ; Puschhof, J.DKFZ* ; Reitsam, N. G. ; Boonekamp, K. E.DKFZ* ; Betge, J.DKFZ* ; Ormanns, S. ; Boutros, M.DKFZ* ; Jackstadt, R.-F. (Last author)DKFZ*
WNT-driven immune evasion promotes malignant transformation of BRAF-mutant colorectal cancer.
Gastroenterology nn, nn (2026) [10.1053/j.gastro.2026.07.035]2026
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