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000119222 0247_ $$2doi$$a10.1007/s00330-016-4323-5
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000119222 0247_ $$2ISSN$$a0938-7994
000119222 0247_ $$2ISSN$$a1432-1084
000119222 0247_ $$2ISSN$$a1613-3749
000119222 0247_ $$2ISSN$$a1613-3757
000119222 037__ $$aDKFZ-2017-00012
000119222 041__ $$aeng
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000119222 1001_ $$aWrede, Karsten H$$b0
000119222 245__ $$aNon-enhanced magnetic resonance imaging of unruptured intracranial aneurysms at 7 Tesla: Comparison with digital subtraction angiography.
000119222 260__ $$aBerlin$$bSpringer$$c2017
000119222 3367_ $$2DRIVER$$aarticle
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000119222 520__ $$aTo prospectively evaluate non-contrast-enhanced 7-Tesla (T) MRA for delineation of unruptured intracranial aneurysms (UIAs) in comparison with DSA.Forty patients with single or multiple UIAs were enrolled in this IRB-approved trial. Sequences acquired at 7 T were TOF MRA and non-contrast-enhanced MPRAGE. All patients additionally underwent 3D rotational DSA. Two neuroradiologists individually analysed the following aneurysm and image features on a five-point scale in 2D and 3D image reconstructions: delineation of parent vessel, dome and neck; overall image quality; presence of artefacts. Interobserver accordance was assessed by the kappa coefficient.A total of 64 UIAs were detected in DSA and in all 2D and 3D MRA image reconstructions. Ratings showed comparable results for DSA and 7-T MRA when considering all image reconstructions. Highest ratings for individual image reconstructions were given for 2D MPRAGE and 3D TOF MRA. Interobserver accordance was almost perfect for the majority of ratings.This study demonstrates excellent delineation of UIAs using 7-T MRA within a clinical setting comparable to the gold standard, DSA. The combination of 7-T non-enhanced MPRAGE and TOF MRA for assessment of untreated UIAs is a promising clinical application of ultra-high-field MRA.• Non-enhanced 7-T MRA allowed excellent delineation of unruptured intracranial aneurysms (UIAs). • Image quality at 7-T was comparable with DSA considering both sequences. • Assessment of UIAs is a promising clinical application of ultra-high-field MRA.
000119222 536__ $$0G:(DE-HGF)POF3-315$$a315 - Imaging and radiooncology (POF3-315)$$cPOF3-315$$fPOF III$$x0
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000119222 7001_ $$aMatsushige, Toshinori$$b1
000119222 7001_ $$aGoericke, Sophia L$$b2
000119222 7001_ $$aChen, Bixia$$b3
000119222 7001_ $$aUmutlu, Lale$$b4
000119222 7001_ $$aQuick, Harald H$$b5
000119222 7001_ $$0P:(DE-He78)022611a2317e4de40fd912e0a72293a8$$aLadd, Mark$$b6$$udkfz
000119222 7001_ $$aJohst, Sören$$b7
000119222 7001_ $$aForsting, Michael$$b8
000119222 7001_ $$aSure, Ulrich$$b9
000119222 7001_ $$aSchlamann, Marc$$b10
000119222 773__ $$0PERI:(DE-600)1472718-3$$a10.1007/s00330-016-4323-5$$gVol. 27, no. 1, p. 354 - 364$$n1$$p354 - 364$$tEuropean radiology$$v27$$x1432-1084$$y2017
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000119222 9141_ $$y2017
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