% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Wrede:119222,
      author       = {K. H. Wrede and T. Matsushige and S. L. Goericke and B.
                      Chen and L. Umutlu and H. H. Quick and M. Ladd$^*$ and S.
                      Johst and M. Forsting and U. Sure and M. Schlamann},
      title        = {{N}on-enhanced magnetic resonance imaging of unruptured
                      intracranial aneurysms at 7 {T}esla: {C}omparison with
                      digital subtraction angiography.},
      journal      = {European radiology},
      volume       = {27},
      number       = {1},
      issn         = {1432-1084},
      address      = {Berlin},
      publisher    = {Springer},
      reportid     = {DKFZ-2017-00012},
      pages        = {354 - 364},
      year         = {2017},
      abstract     = {To prospectively evaluate non-contrast-enhanced 7-Tesla (T)
                      MRA for delineation of unruptured intracranial aneurysms
                      (UIAs) in comparison with DSA.Forty patients with single or
                      multiple UIAs were enrolled in this IRB-approved trial.
                      Sequences acquired at 7 T were TOF MRA and
                      non-contrast-enhanced MPRAGE. All patients additionally
                      underwent 3D rotational DSA. Two neuroradiologists
                      individually analysed the following aneurysm and image
                      features on a five-point scale in 2D and 3D image
                      reconstructions: delineation of parent vessel, dome and
                      neck; overall image quality; presence of artefacts.
                      Interobserver accordance was assessed by the kappa
                      coefficient.A total of 64 UIAs were detected in DSA and in
                      all 2D and 3D MRA image reconstructions. Ratings showed
                      comparable results for DSA and 7-T MRA when considering all
                      image reconstructions. Highest ratings for individual image
                      reconstructions were given for 2D MPRAGE and 3D TOF MRA.
                      Interobserver accordance was almost perfect for the majority
                      of ratings.This study demonstrates excellent delineation of
                      UIAs using 7-T MRA within a clinical setting comparable to
                      the gold standard, DSA. The combination of 7-T non-enhanced
                      MPRAGE and TOF MRA for assessment of untreated UIAs is a
                      promising clinical application of ultra-high-field MRA.•
                      Non-enhanced 7-T MRA allowed excellent delineation of
                      unruptured intracranial aneurysms (UIAs). • Image quality
                      at 7-T was comparable with DSA considering both sequences.
                      • Assessment of UIAs is a promising clinical application
                      of ultra-high-field MRA.},
      cin          = {E020},
      ddc          = {610},
      cid          = {I:(DE-He78)E020-20160331},
      pnm          = {315 - Imaging and radiooncology (POF3-315)},
      pid          = {G:(DE-HGF)POF3-315},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:26993650},
      doi          = {10.1007/s00330-016-4323-5},
      url          = {https://inrepo02.dkfz.de/record/119222},
}