TY  - JOUR
AU  - Volckmar, Anna-Lena
AU  - Leichsenring, Jonas
AU  - Flechtenmacher, Christa
AU  - Pfarr, Nicole
AU  - Siebolts, Udo
AU  - Kirchner, Martina
AU  - Budczies, Jan
AU  - Bockmayr, Michael
AU  - Ridinger, Kathrin
AU  - Lorenz, Katja
AU  - Herpel, Esther
AU  - Noske, Aurelia
AU  - Weichert, Wilko
AU  - Klauschen, Frederick
AU  - Schirmacher, Peter
AU  - Penzel, Roland
AU  - Endris, Volker
AU  - Stenzinger, Albrecht
TI  - Tubular, lactating, and ductal adenomas are devoid of MED12 Exon2 mutations, and ductal adenomas show recurrent mutations in GNAS and the PI3K-AKT pathway
JO  - Genes, chromosomes & cancer
VL  - 56
IS  - 1
SN  - 1045-2257
CY  - New York, NY
PB  - Wiley-Liss
M1  - DKFZ-2017-00014
SP  - 11 - 17
PY  - 2017
AB  - Adenomas of the breast are rare benign tumors although single cases with malignant behavior have been reported. However, the genetic basis of these tumors is unknown. Employing targeted next generation sequencing of 50 cancer-related genes as well as Sanger sequencing, we profiled a cohort of 18 mammary adenomas comprising 9 ductal, 6 tubular, and 3 lactating adenoma. Missense mutations were detected in 8 of the 18 cases (44
LB  - PUB:(DE-HGF)16
C6  - pmid:27438523
DO  - DOI:10.1002/gcc.22396
UR  - https://inrepo02.dkfz.de/record/119224
ER  -