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000119232 0247_ $$2doi$$a10.1016/j.ejrad.2016.11.007
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000119232 037__ $$aDKFZ-2017-00022
000119232 041__ $$aeng
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000119232 1001_ $$aBeiderwellen, Karsten$$b0
000119232 245__ $$aContrast enhanced renal MR angiography at 7 Tesla: How much gadolinium do we need?
000119232 260__ $$aAmsterdam [u.a.]$$bElsevier Science$$c2017
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000119232 520__ $$aTo investigate whether a dose reduction of Gadobutrol for renal magnetic resonance angiography (MRA) at 7 Tesla (T) is feasible while preserving diagnostic image quality.Ten healthy volunteers were enrolled for a renal MRA on a 7T scanner. Fast low angle shot (FLASH) MRA data sets were obtained utilizing three different doses of Gadobutrol (0.1, 0.05 and 0.025mmol/kg body weight [BW]). Contrast ratios (CR) were measured in the aorta as well as in the intra- and extraparenchymal arteries compared to the psoas muscle. Qualitative analysis regarding the delineation of vessel structures was performed using a four-point-scale.All doses of Gadobutrol allowed for a good delineation of the aorta and renal arteries. For the extra- and intraparenchymal segmental arteries higher values were observed for full and half dose in comparison to quarter dose. No significant difference was observed for full and half dose. A lower CR was observed for quarter compared to half dose (p<0.05) for the renal arteries.While best results were observed for half and full dose, a dose reduction to 0.025mmol/kg BW is justifiable, maintaining a diagnostic image quality. This may be of high interest considering patients with renal impairment.
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000119232 7001_ $$aKraff, Oliver$$b1
000119232 7001_ $$aLaader, Anja$$b2
000119232 7001_ $$aMaderwald, Stefan$$b3
000119232 7001_ $$aOrzada, Stephan$$b4
000119232 7001_ $$0P:(DE-He78)022611a2317e4de40fd912e0a72293a8$$aLadd, Mark$$b5$$udkfz
000119232 7001_ $$aForsting, Michael$$b6
000119232 7001_ $$aLauenstein, Thomas C$$b7
000119232 7001_ $$aUmutlu, Lale$$b8
000119232 773__ $$0PERI:(DE-600)2005350-2$$a10.1016/j.ejrad.2016.11.007$$gVol. 86, p. 76 - 82$$p76 - 82$$tEuropean journal of radiology$$v86$$x0720-048X$$y2017
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000119232 9141_ $$y2017
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