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@ARTICLE{Beiderwellen:119232,
      author       = {K. Beiderwellen and O. Kraff and A. Laader and S. Maderwald
                      and S. Orzada and M. Ladd$^*$ and M. Forsting and T. C.
                      Lauenstein and L. Umutlu},
      title        = {{C}ontrast enhanced renal {MR} angiography at 7 {T}esla:
                      {H}ow much gadolinium do we need?},
      journal      = {European journal of radiology},
      volume       = {86},
      issn         = {0720-048X},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier Science},
      reportid     = {DKFZ-2017-00022},
      pages        = {76 - 82},
      year         = {2017},
      abstract     = {To investigate whether a dose reduction of Gadobutrol for
                      renal magnetic resonance angiography (MRA) at 7 Tesla (T) is
                      feasible while preserving diagnostic image quality.Ten
                      healthy volunteers were enrolled for a renal MRA on a 7T
                      scanner. Fast low angle shot (FLASH) MRA data sets were
                      obtained utilizing three different doses of Gadobutrol (0.1,
                      0.05 and 0.025mmol/kg body weight [BW]). Contrast ratios
                      (CR) were measured in the aorta as well as in the intra- and
                      extraparenchymal arteries compared to the psoas muscle.
                      Qualitative analysis regarding the delineation of vessel
                      structures was performed using a four-point-scale.All doses
                      of Gadobutrol allowed for a good delineation of the aorta
                      and renal arteries. For the extra- and intraparenchymal
                      segmental arteries higher values were observed for full and
                      half dose in comparison to quarter dose. No significant
                      difference was observed for full and half dose. A lower CR
                      was observed for quarter compared to half dose (p<0.05) for
                      the renal arteries.While best results were observed for half
                      and full dose, a dose reduction to 0.025mmol/kg BW is
                      justifiable, maintaining a diagnostic image quality. This
                      may be of high interest considering patients with renal
                      impairment.},
      cin          = {E020},
      ddc          = {610},
      cid          = {I:(DE-He78)E020-20160331},
      pnm          = {315 - Imaging and radiooncology (POF3-315)},
      pid          = {G:(DE-HGF)POF3-315},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:28027770},
      doi          = {10.1016/j.ejrad.2016.11.007},
      url          = {https://inrepo02.dkfz.de/record/119232},
}