Home > Publications database > Contrast enhanced renal MR angiography at 7 Tesla: How much gadolinium do we need? > print |
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024 | 7 | _ | |a 10.1016/j.ejrad.2016.11.007 |2 doi |
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037 | _ | _ | |a DKFZ-2017-00022 |
041 | _ | _ | |a eng |
082 | _ | _ | |a 610 |
100 | 1 | _ | |a Beiderwellen, Karsten |b 0 |
245 | _ | _ | |a Contrast enhanced renal MR angiography at 7 Tesla: How much gadolinium do we need? |
260 | _ | _ | |a Amsterdam [u.a.] |c 2017 |b Elsevier Science |
336 | 7 | _ | |a article |2 DRIVER |
336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1511337766_28941 |2 PUB:(DE-HGF) |
336 | 7 | _ | |a ARTICLE |2 BibTeX |
336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
520 | _ | _ | |a To investigate whether a dose reduction of Gadobutrol for renal magnetic resonance angiography (MRA) at 7 Tesla (T) is feasible while preserving diagnostic image quality.Ten healthy volunteers were enrolled for a renal MRA on a 7T scanner. Fast low angle shot (FLASH) MRA data sets were obtained utilizing three different doses of Gadobutrol (0.1, 0.05 and 0.025mmol/kg body weight [BW]). Contrast ratios (CR) were measured in the aorta as well as in the intra- and extraparenchymal arteries compared to the psoas muscle. Qualitative analysis regarding the delineation of vessel structures was performed using a four-point-scale.All doses of Gadobutrol allowed for a good delineation of the aorta and renal arteries. For the extra- and intraparenchymal segmental arteries higher values were observed for full and half dose in comparison to quarter dose. No significant difference was observed for full and half dose. A lower CR was observed for quarter compared to half dose (p<0.05) for the renal arteries.While best results were observed for half and full dose, a dose reduction to 0.025mmol/kg BW is justifiable, maintaining a diagnostic image quality. This may be of high interest considering patients with renal impairment. |
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588 | _ | _ | |a Dataset connected to CrossRef, PubMed, |
700 | 1 | _ | |a Kraff, Oliver |b 1 |
700 | 1 | _ | |a Laader, Anja |b 2 |
700 | 1 | _ | |a Maderwald, Stefan |b 3 |
700 | 1 | _ | |a Orzada, Stephan |b 4 |
700 | 1 | _ | |a Ladd, Mark |0 P:(DE-He78)022611a2317e4de40fd912e0a72293a8 |b 5 |u dkfz |
700 | 1 | _ | |a Forsting, Michael |b 6 |
700 | 1 | _ | |a Lauenstein, Thomas C |b 7 |
700 | 1 | _ | |a Umutlu, Lale |b 8 |
773 | _ | _ | |a 10.1016/j.ejrad.2016.11.007 |g Vol. 86, p. 76 - 82 |0 PERI:(DE-600)2005350-2 |p 76 - 82 |t European journal of radiology |v 86 |y 2017 |x 0720-048X |
909 | C | O | |o oai:inrepo02.dkfz.de:119232 |p VDB |
910 | 1 | _ | |a Deutsches Krebsforschungszentrum |0 I:(DE-588b)2036810-0 |k DKFZ |b 5 |6 P:(DE-He78)022611a2317e4de40fd912e0a72293a8 |
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914 | 1 | _ | |y 2017 |
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