%0 Journal Article
%A Bickelhaupt, Sebastian
%A Tesdorff, Jana
%A Laun, Frederik
%A Kuder, Tristan Anselm
%A Lederer, Wolfgang
%A Teiner, Susanne
%A Maier-Hein, Klaus
%A Daniel, Heidi
%A Stieber, Anne
%A Delorme, Stefan
%A Schlemmer, Heinz-Peter
%T Independent value of image fusion in unenhanced breast MRI using diffusion-weighted and morphological T2-weighted images for lesion characterization in patients with recently detected BI-RADS 4/5 x-ray mammography findings.
%J European radiology
%V 27
%N 2
%@ 1432-1084
%C Berlin
%I Springer
%M DKFZ-2017-00024
%P 562 - 569
%D 2017
%X The aim of this study was to evaluate the accuracy and applicability of solitarily reading fused image series of T2-weighted and high-b-value diffusion-weighted sequences for lesion characterization as compared to sequential or combined image analysis of these unenhanced sequences and to contrast- enhanced breast MRI.This IRB-approved study included 50 female participants with suspicious breast lesions detected in screening X-ray mammograms, all of which provided written informed consent. Prior to biopsy, all women underwent MRI including diffusion-weighted imaging (DWIBS, b = 1500s/mm(2)). Images were analyzed as follows: prospective image fusion of DWIBS and T2-weighted images (FU), side-by-side analysis of DWIBS and T2-weighted series (CO), combination of the first two methods (CO+FU), and full contrast-enhanced diagnostic protocol (FDP). Diagnostic indices, confidence, and image quality of the protocols were compared by two blinded readers.Reading the CO+FU (accuracy 0.92; NPV 96.1 
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:27193776
%R 10.1007/s00330-016-4400-9
%U https://inrepo02.dkfz.de/record/119234