TY  - JOUR
AU  - Bickelhaupt, Sebastian
AU  - Tesdorff, Jana
AU  - Laun, Frederik
AU  - Kuder, Tristan Anselm
AU  - Lederer, Wolfgang
AU  - Teiner, Susanne
AU  - Maier-Hein, Klaus
AU  - Daniel, Heidi
AU  - Stieber, Anne
AU  - Delorme, Stefan
AU  - Schlemmer, Heinz-Peter
TI  - Independent value of image fusion in unenhanced breast MRI using diffusion-weighted and morphological T2-weighted images for lesion characterization in patients with recently detected BI-RADS 4/5 x-ray mammography findings.
JO  - European radiology
VL  - 27
IS  - 2
SN  - 1432-1084
CY  - Berlin
PB  - Springer
M1  - DKFZ-2017-00024
SP  - 562 - 569
PY  - 2017
AB  - The aim of this study was to evaluate the accuracy and applicability of solitarily reading fused image series of T2-weighted and high-b-value diffusion-weighted sequences for lesion characterization as compared to sequential or combined image analysis of these unenhanced sequences and to contrast- enhanced breast MRI.This IRB-approved study included 50 female participants with suspicious breast lesions detected in screening X-ray mammograms, all of which provided written informed consent. Prior to biopsy, all women underwent MRI including diffusion-weighted imaging (DWIBS, b = 1500s/mm(2)). Images were analyzed as follows: prospective image fusion of DWIBS and T2-weighted images (FU), side-by-side analysis of DWIBS and T2-weighted series (CO), combination of the first two methods (CO+FU), and full contrast-enhanced diagnostic protocol (FDP). Diagnostic indices, confidence, and image quality of the protocols were compared by two blinded readers.Reading the CO+FU (accuracy 0.92; NPV 96.1 
LB  - PUB:(DE-HGF)16
C6  - pmid:27193776
DO  - DOI:10.1007/s00330-016-4400-9
UR  - https://inrepo02.dkfz.de/record/119234
ER  -