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| 024 | 7 | _ | |a 10.1007/s00330-016-4400-9 |2 doi |
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| 024 | 7 | _ | |a 0938-7994 |2 ISSN |
| 024 | 7 | _ | |a 1432-1084 |2 ISSN |
| 024 | 7 | _ | |a 1613-3749 |2 ISSN |
| 024 | 7 | _ | |a 1613-3757 |2 ISSN |
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| 082 | _ | _ | |a 610 |
| 100 | 1 | _ | |a Bickelhaupt, Sebastian |0 P:(DE-He78)d2d971750bce6217eb90fff9b01e61f9 |b 0 |e First author |u dkfz |
| 245 | _ | _ | |a Independent value of image fusion in unenhanced breast MRI using diffusion-weighted and morphological T2-weighted images for lesion characterization in patients with recently detected BI-RADS 4/5 x-ray mammography findings. |
| 260 | _ | _ | |a Berlin |c 2017 |b Springer |
| 336 | 7 | _ | |a article |2 DRIVER |
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| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1511336942_29010 |2 PUB:(DE-HGF) |
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| 520 | _ | _ | |a The aim of this study was to evaluate the accuracy and applicability of solitarily reading fused image series of T2-weighted and high-b-value diffusion-weighted sequences for lesion characterization as compared to sequential or combined image analysis of these unenhanced sequences and to contrast- enhanced breast MRI.This IRB-approved study included 50 female participants with suspicious breast lesions detected in screening X-ray mammograms, all of which provided written informed consent. Prior to biopsy, all women underwent MRI including diffusion-weighted imaging (DWIBS, b = 1500s/mm(2)). Images were analyzed as follows: prospective image fusion of DWIBS and T2-weighted images (FU), side-by-side analysis of DWIBS and T2-weighted series (CO), combination of the first two methods (CO+FU), and full contrast-enhanced diagnostic protocol (FDP). Diagnostic indices, confidence, and image quality of the protocols were compared by two blinded readers.Reading the CO+FU (accuracy 0.92; NPV 96.1 %; PPV 87.6 %) and the CO series (0.90; 96.1 %; 83.7 %) provided a diagnostic performance similar to the FDP (0.95; 96.1 %; 91.3 %; p > 0.05). FU reading alone significantly reduced the diagnostic accuracy (0.82; 93.3 %; 73.4 %; p = 0.023).MR evaluation of suspicious BI-RADS 4 and 5 lesions detected on mammography by using a non-contrast-enhanced T2-weighted and DWIBS sequence protocol is most accurate if MR images were read using the CO+FU protocol.• Unenhanced breast MRI with additional DWIBS/T2w-image fusion allows reliable lesion characterization. • Abbreviated reading of fused DWIBS/T2w-images alone decreases diagnostic confidence and accuracy. • Reading fused DWIBS/T2w-images as the sole diagnostic method should be avoided. |
| 536 | _ | _ | |a 315 - Imaging and radiooncology (POF3-315) |0 G:(DE-HGF)POF3-315 |c POF3-315 |f POF III |x 0 |
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| 700 | 1 | _ | |a Tesdorff, Jana |0 P:(DE-He78)9ee50e56e74008d0e0e368b28b0e8b4f |b 1 |u dkfz |
| 700 | 1 | _ | |a Laun, Frederik |0 P:(DE-He78)b709e6df1ec6b63e5ffad4c8131f6f4d |b 2 |u dkfz |
| 700 | 1 | _ | |a Kuder, Tristan Anselm |0 P:(DE-He78)59dfdd0ee0a7f0db81535f0781a3a6d6 |b 3 |u dkfz |
| 700 | 1 | _ | |a Lederer, Wolfgang |b 4 |
| 700 | 1 | _ | |a Teiner, Susanne |b 5 |
| 700 | 1 | _ | |a Maier-Hein, Klaus |0 P:(DE-He78)33c74005e1ce56f7025c4f6be15321b3 |b 6 |u dkfz |
| 700 | 1 | _ | |a Daniel, Heidi |b 7 |
| 700 | 1 | _ | |a Stieber, Anne |0 P:(DE-HGF)0 |b 8 |
| 700 | 1 | _ | |a Delorme, Stefan |0 P:(DE-He78)3e76653311420a51a5faeb80363bd73e |b 9 |u dkfz |
| 700 | 1 | _ | |a Schlemmer, Heinz-Peter |0 P:(DE-He78)3d04c8fee58c9ab71f62ff80d06b6fec |b 10 |e Last author |u dkfz |
| 773 | _ | _ | |a 10.1007/s00330-016-4400-9 |g Vol. 27, no. 2, p. 562 - 569 |0 PERI:(DE-600)1472718-3 |n 2 |p 562 - 569 |t European radiology |v 27 |y 2017 |x 1432-1084 |
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