TY  - JOUR
AU  - Buffart, Laurien M
AU  - Kalter, Joeri
AU  - Sweegers, Maike G
AU  - Courneya, Kerry S
AU  - Newton, Robert U
AU  - Aaronson, Neil K
AU  - Jacobsen, Paul B
AU  - May, Anne M
AU  - Galvão, Daniel A
AU  - Chinapaw, Mai J
AU  - Steindorf, Karen
AU  - Irwin, Melinda L
AU  - Stuiver, Martijn M
AU  - Hayes, Sandi
AU  - Griffith, Kathleen A
AU  - Lucia, Alejandro
AU  - Mesters, Ilse
AU  - van Weert, Ellen
AU  - Knoop, Hans
AU  - Goedendorp, Martine M
AU  - Mutrie, Nanette
AU  - Daley, Amanda J
AU  - McConnachie, Alex
AU  - Bohus, Martin
AU  - Thorsen, Lene
AU  - Schulz, Karl-Heinz
AU  - Short, Camille E
AU  - James, Erica L
AU  - Plotnikoff, Ron C
AU  - Arbane, Gill
AU  - Schmidt, Martina
AU  - Potthoff, Karin
AU  - van Beurden, Marc
AU  - Oldenburg, Hester S
AU  - Sonke, Gabe S
AU  - van Harten, Wim H
AU  - Garrod, Rachel
AU  - Schmitz, Kathryn H
AU  - Winters-Stone, Kerri M
AU  - Velthuis, Miranda J
AU  - Taaffe, Dennis R
AU  - van Mechelen, Willem
AU  - Kersten, Marie-José
AU  - Nollet, Frans
AU  - Wenzel, Jennifer
AU  - Wiskemann, Joachim
AU  - Verdonck-de Leeuw, Irma M
AU  - Brug, Johannes
TI  - Effects and moderators of exercise on quality of life and physical function in patients with cancer: An individual patient data meta-analysis of 34 RCTs.
JO  - Cancer treatment reviews
VL  - 52
SN  - 0305-7372
CY  - Amsterdam [u.a.]
PB  - Elsevier
M1  - DKFZ-2017-00026
SP  - 91 - 104
PY  - 2017
AB  - This individual patient data meta-analysis aimed to evaluate the effects of exercise on quality of life (QoL) and physical function (PF) in patients with cancer, and to identify moderator effects of demographic (age, sex, marital status, education), clinical (body mass index, cancer type, presence of metastasis), intervention-related (intervention timing, delivery mode and duration, and type of control group), and exercise-related (exercise frequency, intensity, type, time) characteristics. Relevant published and unpublished studies were identified in September 2012 via PubMed, EMBASE, PsycINFO, and CINAHL, reference checking and personal communications. Principle investigators of all 69 eligible trials were requested to share IPD from their study. IPD from 34 randomised controlled trials (n=4519 patients) that evaluated the effects of exercise compared to a usual care, wait-list or attention control group on QoL and PF in adult patients with cancer were retrieved and pooled. Linear mixed-effect models were used to evaluate the effects of the exercise on post-intervention outcome values (z-score) adjusting for baseline values. Moderator effects were studies by testing interactions. Exercise significantly improved QoL (β=0.15, 95
LB  - PUB:(DE-HGF)16
C6  - pmid:28006694
DO  - DOI:10.1016/j.ctrv.2016.11.010
UR  - https://inrepo02.dkfz.de/record/119236
ER  -