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000119258 0247_ $$2doi$$a10.1080/01635581.2017.1265131
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000119258 0247_ $$2ISSN$$a0163-5581
000119258 0247_ $$2ISSN$$a1532-7914
000119258 037__ $$aDKFZ-2017-00044
000119258 041__ $$aeng
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000119258 1001_ $$aSkender, Stephanie$$b0
000119258 245__ $$aPlasma 25-Hydroxyvitamin D3 Levels in Colorectal Cancer Patients and Associations with Physical Activity.
000119258 260__ $$aNew York, NY$$bRoutledge, Taylor & Francis Group$$c2017
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000119258 520__ $$aPhysical activity (PA) and vitamin D are thought to affect colorectal cancer prognosis. The present study investigates associations between 25(OH)D3 and PA in prospectively followed colorectal cancer patients in the ColoCare study. At 6, 12, and 24 mo after surgery, patients donated a blood sample, wore an accelerometer for 10 consecutive days, and completed a PA questionnaire. Plasma 25-hydroxyvitamin D3 (25(OH)D3) levels were measured by high-performance liquid chromatography. We tested associations using partial correlations and multivariate linear regression analysis, adjusted for season, age, and body mass index. A total of 137 assessments of 25(OH)D3 levels and PA were conducted (58 at 6 mo, 51 at 12 mo, and 28 at 24 mo). More than 60% of the patients were vitamin D-deficient (25(OH)D3 ≤20 ng/ml), independent of study time point. At 6-mo follow-up, accelerometry-based vigorous and moderate-to-vigorous PAs were positively associated with 25(OH)D3 levels (P = 0.04; P = 0.006,). PA together with season was a significant predictor of elevated 25(OH)D3 levels. Our results suggest that the majority of colorectal cancer patients may suffer from vitamin D deficiency. Engaging in PA may be an effective approach to increase their 25(OH)D3 levels.
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000119258 7001_ $$aBöhm, Jürgen$$b1
000119258 7001_ $$0P:(DE-He78)01ef71f71b01a3ec3b698653fd43fe86$$aSchrotz-King, Petra$$b2
000119258 7001_ $$0P:(DE-He78)c259d6cc99edf5c7bc7ce22c7f87c253$$aChang, Jenny$$b3
000119258 7001_ $$aSiegel, Erin M$$b4
000119258 7001_ $$0P:(DE-He78)a0c2037d9054be26907a05ae520d5756$$aSteindorf, Karen$$b5
000119258 7001_ $$0P:(DE-He78)43996fb100428b0d99e233c3261f7187$$aOwen, Robert$$b6$$udkfz
000119258 7001_ $$aOse, Jennifer$$b7
000119258 7001_ $$0P:(DE-He78)6c5d058b7552d071a7fa4c5e943fff0f$$aHoffmeister, Michael$$b8
000119258 7001_ $$0P:(DE-He78)90d5535ff896e70eed81f4a4f6f22ae2$$aBrenner, Hermann$$b9
000119258 7001_ $$aUlrich, Cornelia M$$b10
000119258 773__ $$0PERI:(DE-600)2025822-7$$a10.1080/01635581.2017.1265131$$gVol. 69, no. 2, p. 229 - 237$$n2$$p229 - 237$$tNutrition and cancer$$v69$$x1532-7914$$y2017
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