%0 Journal Article
%A Kucab, Jill E
%A Hollstein, Monica
%A Arlt, Volker M
%A Phillips, David H
%T Nutlin-3a selects for cells harbouring TP53 mutations.
%J International journal of cancer
%V 140
%N 4
%@ 0020-7136
%C Bognor Regis
%I Wiley-Liss
%M DKFZ-2017-00052
%P 877 - 887
%D 2017
%X TP53 mutations occur in half of all human tumours. Mutagen-induced or spontaneous TP53 mutagenesis can be studied in vitro using the human TP53 knock-in (Hupki) mouse embryo fibroblast (HUF) immortalisation assay (HIMA). TP53 mutations arise in up to 30
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:27813088
%2 pmc:PMC5215675
%R 10.1002/ijc.30504
%U https://inrepo02.dkfz.de/record/119266