TY  - JOUR
AU  - Kucab, Jill E
AU  - Hollstein, Monica
AU  - Arlt, Volker M
AU  - Phillips, David H
TI  - Nutlin-3a selects for cells harbouring TP53 mutations.
JO  - International journal of cancer
VL  - 140
IS  - 4
SN  - 0020-7136
CY  - Bognor Regis
PB  - Wiley-Liss
M1  - DKFZ-2017-00052
SP  - 877 - 887
PY  - 2017
AB  - TP53 mutations occur in half of all human tumours. Mutagen-induced or spontaneous TP53 mutagenesis can be studied in vitro using the human TP53 knock-in (Hupki) mouse embryo fibroblast (HUF) immortalisation assay (HIMA). TP53 mutations arise in up to 30
LB  - PUB:(DE-HGF)16
C6  - pmid:27813088
C2  - pmc:PMC5215675
DO  - DOI:10.1002/ijc.30504
UR  - https://inrepo02.dkfz.de/record/119266
ER  -