TY - JOUR AU - Böck, Barbara AU - Stein, Ulrike AU - Schmitt, Clemens A AU - Augustin, Hellmut TI - Mouse models of human cancer. JO - Cancer research VL - 74 IS - 17 SN - 1538-7445 CY - Philadelphia, Pa. PB - AACR M1 - DKFZ-2017-00301 SP - 4671 - 4675 PY - 2014 AB - The Helmholtz Alliance Preclinical Comprehensive Cancer Center (PCCC; www.helmholtz-pccc.de) hosted the '1st International Kloster Seeon Meeting on Mouse Models of Human Cancer' in the Seeon monastery (Germany) from March 8 to 11, 2014. The meeting focused on the development and application of novel mouse models in tumor research and high-throughput technologies to overcome one of the most critical bottlenecks in translational bench-to-bedside tumor biology research. Moreover, the participants discussed basic molecular mechanisms underlying tumor initiation, progression, metastasis, and therapy resistance, which are the prerequisite for the development of novel treatment strategies and clinical applications in cancer therapy. LB - PUB:(DE-HGF)16 C6 - pmid:25136075 DO - DOI:10.1158/0008-5472.CAN-14-1424 UR - https://inrepo02.dkfz.de/record/119670 ER -