TY  - JOUR
AU  - Caers, Jo
AU  - Withofs, Nadia
AU  - Hillengass, Jens
AU  - Simoni, Paolo
AU  - Zamagni, Elena
AU  - Hustinx, Roland
AU  - Beguin, Yves
TI  - The role of positron emission tomography-computed tomography and magnetic resonance imaging in diagnosis and follow up of multiple myeloma.
JO  - Haematologica
VL  - 99
IS  - 4
SN  - 1592-8721
CY  - Pavia
PB  - Ferrata Storti Foundation
M1  - DKFZ-2017-00347
SP  - 629 - 637
PY  - 2014
AB  - Multiple myeloma is the second most common hematologic malignancy and occurs most commonly in elderly patients. Almost all multiple myeloma patients develop bone lesions in the course of their disease or have evidence of bone loss at initial diagnosis. Whole-body conventional radiography remains the gold standard in the diagnostic evaluation, but computed tomography, magnetic resonance imaging and 18F-fluorodeoxyglucose positron emission tomography are increasingly used as complementary techniques in the detection of bone lesions. Moreover, the number of lesions detected and the presence of extramedullary disease give strong prognostic information. These new techniques may help to assess treatment response in solitary plasmacytoma or in multiple myeloma. In this article, we review recent data on the different imaging techniques used at diagnosis and in the assessment of treatment response, and discuss some current issues.
LB  - PUB:(DE-HGF)16
C6  - pmid:24688111
C2  - pmc:PMC3971072
DO  - DOI:10.3324/haematol.2013.091918
UR  - https://inrepo02.dkfz.de/record/119720
ER  -