TY  - JOUR
AU  - Soffietti, Riccardo
AU  - Abacioglu, Ufuk
AU  - Baumert, Brigitta
AU  - Combs, Stephanie E
AU  - Kinhult, Sara
AU  - Kros, Johan M
AU  - Marosi, Christine
AU  - Metellus, Philippe
AU  - Radbruch, Alexander
AU  - Villa Freixa, Salvador S
AU  - Brada, Michael
AU  - Carapella, Carmine M
AU  - Preusser, Matthias
AU  - Le Rhun, Emilie
AU  - Rudà, Roberta
AU  - Tonn, Joerg C
AU  - Weber, Damien C
AU  - Weller, Michael
TI  - Diagnosis and treatment of brain metastases from solid tumors: guidelines from the European Association of Neuro-Oncology (EANO).
JO  - Neuro-Oncology
VL  - 19
IS  - 2
SN  - 1523-5866
CY  - Oxford
PB  - Oxford Univ. Press
M1  - DKFZ-2017-00928
SP  - 162 - 174
PY  - 2017
AB  - The management of patients with brain metastases has become a major issue due to the increasing frequency and complexity of the diagnostic and therapeutic approaches. In 2014, the European Association of Neuro-Oncology (EANO) created a multidisciplinary Task Force to draw evidence-based guidelines for patients with brain metastases from solid tumors. Here, we present these guidelines, which provide a consensus review of evidence and recommendations for diagnosis by neuroimaging and neuropathology, staging, prognostic factors, and different treatment options. Specifically, we addressed options such as surgery, stereotactic radiosurgery/stereotactic fractionated radiotherapy, whole-brain radiotherapy, chemotherapy and targeted therapy (with particular attention to brain metastases from non-small cell lung cancer, melanoma and breast and renal cancer), and supportive care.
LB  - PUB:(DE-HGF)16
C6  - pmid:28391295
DO  - DOI:10.1093/neuonc/now241
UR  - https://inrepo02.dkfz.de/record/120499
ER  -