TY  - JOUR
AU  - Klassen, Oliver
AU  - Schmidt, Martina
AU  - Scharhag-Rosenberger, Friederike
AU  - Ulrich, Cornelia M
AU  - Schneeweiss, Andreas
AU  - Potthoff, Karin
AU  - Steindorf, Karen
AU  - Wiskemann, Joachim
TI  - Muscle strength in breast cancer patients receiving different treatment regimes.
JO  - Journal of cachexia, sarcopenia and muscle
VL  - 8
IS  - 2
SN  - 2190-5991
CY  - Hoboken, NJ
PB  - Wiley
M1  - DKFZ-2017-01248
SP  - 305 - 316
PY  - 2017
N1  - Scharhag-Rosenberger, F, Sorkin, M not imported
AB  - Muscle dysfunction and sarcopenia have been associated with poor performance status, an increased mortality risk, and greater side effects in oncologic patients. However, little is known about how performance is affected by cancer therapy. We investigated muscle strength in breast cancer patients in different adjuvant treatment settings and also compared it with data from healthy individuals.Breast cancer patients (N = 255) from two randomized controlled exercise trials, staged 0-III and aged 54.4 ± 9.4 years, were categorized into four groups according to their treatment status. In a cross-sectional design, muscle function was assessed bilaterally by isokinetic dynamometry (0°, 60°, 180°/s) as maximal voluntary isometric contraction (MVIC) and maximal isokinetic peak torque (MIPT) in shoulder rotators and knee flexors and extensors. Additionally, muscular fatigue index (FI
LB  - PUB:(DE-HGF)16
C6  - pmid:27896952
C2  - pmc:PMC5377413
DO  - DOI:10.1002/jcsm.12165
UR  - https://inrepo02.dkfz.de/record/124369
ER  -