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@ARTICLE{Klemm:124370,
      author       = {M. Klemm and T. Kirchner$^*$ and J. Gröhl$^*$ and D.
                      Cheray$^*$ and M. Nolden$^*$ and A. Seitel$^*$ and H. Hoppe
                      and L. Maier-Hein$^*$ and A. Franz$^*$},
      title        = {{MITK}-{O}pen{IGTL}ink for combining open-source toolkits
                      in real-time computer-assisted interventions.},
      journal      = {International journal of computer assisted radiology and
                      surgery},
      volume       = {12},
      number       = {3},
      issn         = {1861-6429},
      address      = {Berlin},
      publisher    = {Springer},
      reportid     = {DKFZ-2017-01249},
      pages        = {351 - 361},
      year         = {2017},
      abstract     = {Due to rapid developments in the research areas of medical
                      imaging, medical image processing and robotics,
                      computer-assisted interventions (CAI) are becoming an
                      integral part of modern patient care. From a software
                      engineering point of view, these systems are highly complex
                      and research can benefit greatly from reusing software
                      components. This is supported by a number of open-source
                      toolkits for medical imaging and CAI such as the medical
                      imaging interaction toolkit (MITK), the public software
                      library for ultrasound imaging research (PLUS) and 3D
                      Slicer. An independent inter-toolkit communication such as
                      the open image-guided therapy link (OpenIGTLink) can be used
                      to combine the advantages of these toolkits and enable an
                      easier realization of a clinical CAI
                      workflow.MITK-OpenIGTLink is presented as a network
                      interface within MITK that allows easy to use, asynchronous
                      two-way messaging between MITK and clinical devices or other
                      toolkits. Performance and interoperability tests with
                      MITK-OpenIGTLink were carried out considering the whole CAI
                      workflow from data acquisition over processing to
                      visualization.We present how MITK-OpenIGTLink can be applied
                      in different usage scenarios. In performance tests, tracking
                      data were transmitted with a frame rate of up to 1000 Hz
                      and a latency of 2.81 ms. Transmission of images with
                      typical ultrasound (US) and greyscale high-definition (HD)
                      resolutions of [Formula: see text] and [Formula: see text]
                      is possible at up to 512 and 128 Hz, respectively.With the
                      integration of OpenIGTLink into MITK, this protocol is now
                      supported by all established open-source toolkits in the
                      field. This eases interoperability between MITK and toolkits
                      such as PLUS or 3D Slicer and facilitates cross-toolkit
                      research collaborations. MITK and its submodule
                      MITK-OpenIGTLink are provided open source under a BSD-style
                      licence ( http://mitk.org ).},
      cin          = {E131 / E130},
      ddc          = {610},
      cid          = {I:(DE-He78)E131-20160331 / I:(DE-He78)E130-20160331},
      pnm          = {315 - Imaging and radiooncology (POF3-315)},
      pid          = {G:(DE-HGF)POF3-315},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:27687984},
      doi          = {10.1007/s11548-016-1488-y},
      url          = {https://inrepo02.dkfz.de/record/124370},
}