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024 7 _ |a 10.1371/journal.pone.0179276
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100 1 _ |a Wagner, Friedrich
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245 _ _ |a Temperature and concentration calibration of aqueous polyvinylpyrrolidone (PVP) solutions for isotropic diffusion MRI phantoms.
260 _ _ |a Lawrence, Kan.
|c 2017
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520 _ _ |a To use the 'apparent diffusion coefficient' (Dapp) as a quantitative imaging parameter, well-suited test fluids are essential. In this study, the previously proposed aqueous solutions of polyvinylpyrrolidone (PVP) were examined and temperature calibrations were obtained. For example, at a temperature of 20°C, Dapp ranged from 1.594 (95% CI: 1.593, 1.595) μm2/ms to 0.3326 (95% CI: 0. 3304, 0.3348) μm2/ms for PVP-concentrations ranging from 10% (w/w) to 50% (w/w) using K30 polymer lengths. The temperature dependence of Dapp was found to be so strong that a negligence seems not advisable. The temperature dependence is descriptively modelled by an exponential function exp(c2 (T - 20°C)) and the determined c2 values are reported, which can be used for temperature calibration. For example, we find the value 0.02952 K-1 for 30% (w/w) PVP-concentration and K30 polymer length. In general, aqueous PVP solutions were found to be suitable to produce easily applicable and reliable Dapp-phantoms.
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700 1 _ |a Laun, Frederik
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700 1 _ |a Kuder, Tristan Anselm
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700 1 _ |a Mlynarska, Anna
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700 1 _ |a Maier, Florian
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700 1 _ |a Faust, Jonas
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700 1 _ |a Demberg, Kerstin
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700 1 _ |a Lindemann, Linus
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700 1 _ |a Rivkin, Boris
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700 1 _ |a Nagel, Armin
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700 1 _ |a Ladd, Mark
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700 1 _ |a Maier-Hein, Klaus
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700 1 _ |a Bickelhaupt, Sebastian
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700 1 _ |a Bach, Michael
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773 _ _ |a 10.1371/journal.pone.0179276
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