TY  - JOUR
AU  - Fellenberg, Jörg
AU  - Sähr, Heiner
AU  - Kunz, Pierre
AU  - Zhao, Zhefu
AU  - Liu, Li
AU  - Tichy, Diana
AU  - Herr, Ingrid
TI  - Restoration of miR-127-3p and miR-376a-3p counteracts the neoplastic phenotype of giant cell tumor of bone derived stromal cells by targeting COA1, GLE1 and PDIA6.
JO  - Cancer letters
VL  - 371
IS  - 1
SN  - 0304-3835
CY  - Amsterdam [u.a.]
PB  - Elsevier Science
M1  - DKFZ-2017-01935
SP  - 134 - 141
PY  - 2016
AB  - Although generally benign, giant cell tumors of bone (GCTB) display an aggressive behavior associated with significant bone destruction and lung metastasis in rare cases. This and the very high recurrence rate observed after surgical resection ranging from 20 to 55
KW  - Gle1 protein, human (NLM Chemicals)
KW  - MIRN127 microRNA, human (NLM Chemicals)
KW  - MIRN376 microRNA, human (NLM Chemicals)
KW  - MicroRNAs (NLM Chemicals)
KW  - Nucleocytoplasmic Transport Proteins (NLM Chemicals)
KW  - PDIA6 protein, human (NLM Chemicals)
KW  - Protein Disulfide-Isomerases (NLM Chemicals)
LB  - PUB:(DE-HGF)16
C6  - pmid:26655997
DO  - DOI:10.1016/j.canlet.2015.10.039
UR  - https://inrepo02.dkfz.de/record/125811
ER  -