TY  - JOUR
AU  - Freitag, Martin
AU  - Radtke, Jan Philipp
AU  - Hadaschik, Boris A
AU  - Kopp-Schneider, Annette
AU  - Eder, Matthias
AU  - Kopka, Klaus
AU  - Haberkorn, Uwe
AU  - Röthke, Matthias
AU  - Schlemmer, Heinz-Peter
AU  - Afshar-Oromieh, Ali
TI  - Comparison of hybrid (68)Ga-PSMA PET/MRI and (68)Ga-PSMA PET/CT in the evaluation of lymph node and bone metastases of prostate cancer.
JO  - European journal of nuclear medicine and molecular imaging
VL  - 43
IS  - 1
SN  - 1619-7089
CY  - Heidelberg [u.a.]
PB  - Springer-Verl.
M1  - DKFZ-2017-01972
SP  - 70 - 83
PY  - 2016
AB  - To evaluate the reproducibility of the combination of hybrid PET/MRI and the (68)Ga-PSMA-11 tracer in depicting lymph node (LN) and bone metastases of prostate cancer (PC) in comparison with that of PET/CT.A retrospective analysis of 26 patients who were subjected to (68)Ga-PSMA PET/CTlow-dose (1 h after injection) followed by PET/MRI (3 h after injection) was performed. MRI sequences included T1-w native, T1-w contrast-enhanced, T2-w fat-saturated and diffusion-weighted sequences (DWIb800). Discordant PET-positive and morphological findings were evaluated. Standardized uptake values (SUV) of PET-positive LNs and bone lesions were quantified and their morphological size and conspicuity determined.Comparing the PET components, the proportion of discordant PSMA-positive suspicious findings was very low (98.5 
KW  - Glu-NH-CO-NH-Lys-(Ahx)-((68)Ga(HBED-CC)) (NLM Chemicals)
KW  - Oligopeptides (NLM Chemicals)
KW  - Edetic Acid (NLM Chemicals)
LB  - PUB:(DE-HGF)16
C6  - pmid:26508290
DO  - DOI:10.1007/s00259-015-3206-3
UR  - https://inrepo02.dkfz.de/record/125848
ER  -