TY - JOUR
AU - Mai, E. K.
AU - Bertsch, U.
AU - Dürig, J.
AU - Kunz, C.
AU - Haenel, M.
AU - Blau, I. W.
AU - Munder, M.
AU - Jauch, A.
AU - Schurich, B.
AU - Hielscher, T.
AU - Merz, M.
AU - Huegle-Doerr, B.
AU - Seckinger, A.
AU - Hose, D.
AU - Hillengass, J.
AU - Raab, M. S.
AU - Neben, K.
AU - Lindemann, H-W
AU - Zeis, M.
AU - Gerecke, C.
AU - Schmidt-Wolf, I. G. H.
AU - Weisel, K.
AU - Scheid, C.
AU - Salwender, H.
AU - Goldschmidt, H.
TI - Phase III trial of bortezomib, cyclophosphamide and dexamethasone (VCD) versus bortezomib, doxorubicin and dexamethasone (PAd) in newly diagnosed myeloma.
JO - Leukemia
VL - 29
IS - 8
SN - 1476-5551
CY - Basingstoke
PB - Nature Publ. Group
M1 - DKFZ-2017-03074
SP - 1721 - 1729
PY - 2015
AB - We aimed at demonstrating non-inferiority of bortezomib/cyclophosphamide/dexamethasone (VCD) compared to bortezomib/doxorubicin/dexamethasone (PAd) induction therapy with respect to very good partial response rates or better (⩾VGPR) in 504 newly diagnosed, transplant-eligible multiple myeloma patients. VCD was found to be non-inferior to PAd with respect to ⩾VGPR rates (37.0 versus 34.3
KW - Boronic Acids (NLM Chemicals)
KW - Pyrazines (NLM Chemicals)
KW - Bortezomib (NLM Chemicals)
KW - Dexamethasone (NLM Chemicals)
KW - Doxorubicin (NLM Chemicals)
KW - Cyclophosphamide (NLM Chemicals)
LB - PUB:(DE-HGF)16
C6 - pmid:25787915
DO - DOI:10.1038/leu.2015.80
UR - https://inrepo02.dkfz.de/record/127048
ER -