%0 Journal Article
%A Radujkovic, Aleksandar
%A Becker, Natalia
%A Benner, Axel
%A Penack, Olaf
%A Platzbecker, Uwe
%A Stölzel, Friedrich
%A Bornhäuser, Martin
%A Hegenbart, Ute
%A Ho, Anthony D
%A Dreger, Peter
%A Luft, Thomas
%T Pre-transplant weight loss predicts inferior outcome after allogeneic stem cell transplantation in patients with myelodysplastic syndrome.
%J OncoTarget
%V 6
%N 33
%@ 1949-2553
%C [S.l.]
%I Impact Journals LLC
%M DKFZ-2017-03371
%P 7406-7420
%D 2015
%X Allogeneic stem cell transplantation (alloSCT) represents a curative therapeutic option for patients with myelodysplastic syndrome (MDS), but relapse and non-relapse mortality (NRM) limit treatment efficacy. Based on our previous observation in acute myeloid leukemia we investigated the impact of pre-transplant weight loss on post-transplant outcome in MDS patients. A total of 111 patients diagnosed with MDS according to WHO criteria transplanted between 2000 and 2012 in three different transplant centers were included into the analysis. Data on weight loss were collected from medical records prior to conditioning therapy and 3-6 months earlier. Patient, disease and transplant characteristics did not differ between patients with weight loss (2-5
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:26360778
%2 pmc:PMC4741512
%R 10.18632/oncotarget.4805
%U https://inrepo02.dkfz.de/record/127346