% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Rengier:127365,
      author       = {F. Rengier$^*$ and M. Delles and J. Eichhorn and Y.-J. Azad
                      and H. von Tengg-Kobligk$^*$ and J. Ley-Zaporozhan and R.
                      Dillmann and H.-U. Kauczor$^*$ and R. Unterhinninghofen and
                      S. Ley},
      title        = {{N}oninvasive 4{D} pressure difference mapping derived from
                      4{D} flow {MRI} in patients with repaired aortic
                      coarctation: comparison with young healthy volunteers.},
      journal      = {The international journal of cardiovascular imaging},
      volume       = {31},
      number       = {4},
      issn         = {1573-0743},
      address      = {Dordrecht [u.a.]},
      publisher    = {Springer},
      reportid     = {DKFZ-2017-03390},
      pages        = {823 - 830},
      year         = {2015},
      abstract     = {To assess spatial and temporal pressure characteristics in
                      patients with repaired aortic coarctation compared to young
                      healthy volunteers using time-resolved velocity-encoded
                      three-dimensional phase-contrast magnetic resonance imaging
                      (4D flow MRI) and derived 4D pressure difference maps. After
                      in vitro validation against invasive catheterization as gold
                      standard, 4D flow MRI of the thoracic aorta was performed at
                      1.5T in 13 consecutive patients after aortic coarctation
                      repair without recoarctation and 13 healthy volunteers.
                      Using in-house developed processing software, 4D pressure
                      difference maps were computed based on the Navier-Stokes
                      equation. Pressure difference amplitudes, maximum slope of
                      pressure amplitudes and spatial pressure range at mid
                      systole were retrospectively measured by three readers, and
                      twice by one reader to assess inter- and intraobserver
                      agreement. In vitro, pressure differences derived from 4D
                      flow MRI showed excellent agreement to invasive catheter
                      measurements. In vivo, pressure difference amplitudes,
                      maximum slope of pressure difference amplitudes and spatial
                      pressure range at mid systole were significantly increased
                      in patients compared to volunteers in the aortic arch, the
                      proximal descending and the distal descending thoracic aorta
                      (p < 0.05). Greatest differences occurred in the proximal
                      descending aorta with values of the three parameters for
                      patients versus volunteers being 19.7 ± 7.5 versus 10.0 ±
                      2.0 (p < 0.001), 10.9 ± 10.4 versus 1.9 ± 0.4 (p = 0.002),
                      and 8.7 ± 6.3 versus 1.6 ± 0.9 (p < 0.001). Inter- and
                      intraobserver agreements were excellent (p < 0.001).
                      Noninvasive 4D pressure difference mapping derived from 4D
                      flow MRI enables detection of altered intraluminal aortic
                      pressures and showed significant spatial and temporal
                      changes in patients with repaired aortic coarctation.},
      cin          = {E010 / E015},
      ddc          = {610},
      cid          = {I:(DE-He78)E010-20160331 / I:(DE-He78)E015-20160331},
      pnm          = {315 - Imaging and radiooncology (POF3-315)},
      pid          = {G:(DE-HGF)POF3-315},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:25645544},
      doi          = {10.1007/s10554-015-0604-3},
      url          = {https://inrepo02.dkfz.de/record/127365},
}