TY  - JOUR
AU  - Wild, Esther
AU  - Bangert, Mark
AU  - Nill, Simeon
AU  - Oelfke, Uwe
TI  - Noncoplanar VMAT for nasopharyngeal tumors: Plan quality versus treatment time.
JO  - Medical physics
VL  - 42
IS  - 5
SN  - 0094-2405
CY  - New York, NY
M1  - DKFZ-2017-03812
SP  - 2157 - 2168
PY  - 2015
AB  - The authors investigated the potential of optimized noncoplanar irradiation trajectories for volumetric modulated arc therapy (VMAT) treatments of nasopharyngeal patients and studied the trade-off between treatment plan quality and delivery time in radiation therapy.For three nasopharyngeal patients, the authors generated treatment plans for nine different delivery scenarios using dedicated optimization methods. They compared these scenarios according to dose characteristics, number of beam directions, and estimated delivery times. In particular, the authors generated the following treatment plans: (1) a 4π plan, which is a not sequenced, fluence optimized plan that uses beam directions from approximately 1400 noncoplanar directions and marks a theoretical upper limit of the treatment plan quality, (2) a coplanar 2π plan with 72 coplanar beam directions as pendant to the noncoplanar 4π plan, (3) a coplanar VMAT plan, (4) a coplanar step and shoot (SnS) plan, (5) a beam angle optimized (BAO) coplanar SnS IMRT plan, (6) a noncoplanar BAO SnS plan, (7) a VMAT plan with rotated treatment couch, (8) a noncoplanar VMAT plan with an optimized great circle around the patient, and (9) a noncoplanar BAO VMAT plan with an arbitrary trajectory around the patient.VMAT using optimized noncoplanar irradiation trajectories reduced the mean and maximum doses in organs at risk compared to coplanar VMAT plans by 19
LB  - PUB:(DE-HGF)16
C6  - pmid:25979010
DO  - DOI:10.1118/1.4914863
UR  - https://inrepo02.dkfz.de/record/127790
ER  -